Loratadine: Difference between revisions

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==Pediatric Dosing==
==Pediatric Dosing==
===[[Allergic rhinitis]]===
===[[Allergic rhinitis]]===
*Children aged 6 and older
*Children aged ≥6 years old
**10 mg PO once daily, OR
**10 mg PO once daily, OR
*Children aged 2 to 5
*Children aged 2 to 5
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===[[Urticaria]]===
===[[Urticaria]]===
*Children aged 6 and older
*Children aged ≥6 years old
**10 mg PO once daily
**10 mg PO once daily
***Some patients may benefit from higher doses. Clinicians should weigh the risks against the benefits.
***Some patients may benefit from higher doses. Clinicians should weigh the risks against the benefits.

Revision as of 21:34, 20 May 2026

Administration

  • Type: H1 antagonists (second generation)
  • Dosage Forms: Tablets (chewable or orally disintegrating tablets [ODTs]), liquid-filled capsules, or a syrup (1 mg/mL solution)
  • Routes of Administration: Oral
  • Common Trade Names: Claritin

Adult Dosing

Allergic rhinitis

  • 10 mg PO once daily, OR
  • 5 mg twice daily
  • Do not exceed 10 mg in 24 hours

Urticaria

  • 10 mg PO once daily
    • Some patients may benefit from higher doses. Clinicians should weigh the risks against the benefits.

Pediatric Dosing

Allergic rhinitis

  • Children aged ≥6 years old
    • 10 mg PO once daily, OR
  • Children aged 2 to 5
    • 5 mg PO once daily
    • Do not exceed 10 mg in 24 hours
    • The ODT formulation is not recommended for younger children.

Urticaria

  • Children aged ≥6 years old
    • 10 mg PO once daily
      • Some patients may benefit from higher doses. Clinicians should weigh the risks against the benefits.

Special Populations

Pregnancy Rating

Lactation risk

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

Comments

See Also

References