Methanol: Difference between revisions

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#REDIRECT[[Methanol toxicity]]
#REDIRECT[[Methanol toxicity]]
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<div style="font-weight:bold;">📊 Osmolal Gap Calculator [show]</div>
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{{Osmolal_Gap_Calculator}}
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Revision as of 13:44, 21 March 2026

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📊 Osmolal Gap Calculator [show]

Osmolal Gap

Serum Osmolal Gap
Parameter Value
Measured Serum Osmolality (mOsm/kg)
Sodium (Na⁺) mEq/L
BUN (mg/dL)
Glucose (mg/dL)
Results
Calculated Osmolality mOsm/kg
Osmolal Gap mOsm/kg
Interpretation
<10 Normal — No significant unmeasured osmoles detected.
>10 Elevated — Consider toxic alcohol ingestion: methanol, ethylene glycol, isopropanol, or other unmeasured osmoles (ethanol, mannitol, contrast dye).
References
  • Smithline N, Gardner KD Jr. Gaps—anionic and osmolal. JAMA. 1976;236(14):1594-1597. PMID 989116.
  • Kraut JA, Xing SX. Approach to the evaluation of a patient with an increased serum osmolal gap and high-anion-gap metabolic acidosis. Am J Kidney Dis. 2011;58(3):480-484. PMID 21794966.
  • Formula: Calculated Osm = 2(Na) + BUN/2.8 + Glucose/18. Gap = Measured − Calculated.