Iodoquinol: Difference between revisions
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*650mg 3 times daily after meals for 20 days | *650mg 3 times daily after meals for 20 days | ||
**Not to exceed 1.95 g daily | **Not to exceed 1.95 g daily | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Iodoquinol]] [[Has Population::Adult]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Children: 30-40mg/kg daily (maximum: 650mg per dose) in 3 divided doses for 20 days | *Children: 30-40mg/kg daily (maximum: 650mg per dose) in 3 divided doses for 20 days | ||
**Not to exceed 1.95 g daily | **Not to exceed 1.95 g daily | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Iodoquinol]] [[Has Population::Pediatric]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 20:38, 20 March 2026
Administration
- Type: Amebicide
- Routes of Administration: Oral
- Common Trade Names: Aloquin; Yodoxin
Adult Dosing
- 650mg 3 times daily after meals for 20 days
- Not to exceed 1.95 g daily
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Acute diarrhea | 650mg q 8hrs daily 20 days | Entamoeba, Luminal |
Pediatric Dosing
- Children: 30-40mg/kg daily (maximum: 650mg per dose) in 3 divided doses for 20 days
- Not to exceed 1.95 g daily
Indications by Disease
Special Populations
- Limited data on use during pregnancy
Renal Dosing
- No adjustments noted by manufacturer
Hepatic Dosing
- No adjustments noted by manufacturer
Contraindications
- Allergy to class/drug, hypersensitivity to iodine and/or 8-hydroxyquinolones
- Concerns with optic neuritis
- Concerns with peripheral neuropathy
- Hepatic impairment
- Renal impairment
- Chronic diarrhea, especially in children
Adverse Reactions
Serious
- Peripheral neuropathy, Long-term (high-dose)
- Optic atrophy, Long-term (high-dose)
- Optic neuritis, Long-term (high-dose)
Common
- Nausea/vomiting, diarrhea, cramps
- Fever/chills
- Pruritus, urticaria
- Headache, dizziness
Pharmacology
- Half-life:
- Metabolism: Liver
- Excretion: Feces, urine
Mechanism of Action
- Contact amebicide that works in the lumen of the intestine (unknown mechanism)
Comments
See Also
References
<UpToDate>