Cefprozil: Difference between revisions
Ostermayer (talk | contribs) No edit summary |
(Add AntibioticDose SMW query table for dynamic indications by disease) |
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Infections, bacterial: | Infections, bacterial: | ||
*250-500mg PO q12h x 10 days | *250-500mg PO q12h x 10 days | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Cefprozil]] [[Has Population::Adult]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
infections, bacterial: | infections, bacterial: | ||
*30mg/kg/day PO divided q12h x 10 days, max 1000mg/day | *30mg/kg/day PO divided q12h x 10 days, max 1000mg/day | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Cefprozil]] [[Has Population::Pediatric]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B | ||
Latest revision as of 20:38, 20 March 2026
Administration
- Type: 2nd generation cephalosporin
- Dosage Forms: tablet, oral suspension
- Dosage Strengths: tablet: 250mg, 500mg; oral suspension: 125mg/5mL, 250mg/5mL
- Routes of Administration: PO
- Common Trade Names: Cefzil
Adult Dosing
Infections, bacterial:
- 250-500mg PO q12h x 10 days
Indications by Disease
Pediatric Dosing
infections, bacterial:
- 30mg/kg/day PO divided q12h x 10 days, max 1000mg/day
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Acute otitis media | 15mg/kg PO BID x7-10 days | Prior Month Treatment |
Special Populations
- Pregnancy Rating: B
- Lactation risk: probably safe
Renal Dosing
- Adult: CrCl < 30: decrease dose 50%
- Pediatric:CrCl < 30: decrease dose 50%
Hepatic Dosing
- Adult: none defined
- Pediatric: none defined
Contraindications
- Allergy to class/drug
- PKU
Adverse Reactions
Serious
- anaphylaxis
- seizures
- nephrotoxicity
- leukopenia or thrombocytopenia
- steven-johnson syndrome
- c-diff associated diarrhea
Common
- nausea
- diarrhea
- vomiting
- transaminitis
- dizziness
- rash
- eosinophilia
Pharmacology
- Half-life: 1.3 h
- Metabolism: hepatic
- Excretion: unchanged in urine (61%)
Mechanism of Action
bactericidal, inhibits cell wall mucopeptide synthesis