Template:Streptococcal Pharyngitis Antibiotics

Treatment can be delayed for up to 9 days and still prevent major sequelae

Penicillin Options:

• Penicillin V 250mg PO BID x 10d (child) or 500mg BID x 10d (adolescent or adult)
• Bicillin L-A <27 kg: 0.6 million units; ≥27 kg: 1.2 million units IM x 1
• Amoxicillin 50 mg/kg once daily (maximum = 1000 mg) for 10 days

Penicillin allergic (mild):

• Cephalexin 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days
• Cefadroxil 30 mg per kg PO QD (maximum 1 g daily) x 10 days

Penicillin allergic (anaphylaxis):

• Clindamycin 7 mg/kg/dose TID (maximum = 300 mg/dose) x 10 days
• Azithromycin 12 mg/kg PO once (maximum = 500 mg), then 6 mg/kg (max=250 mg) once daily for the next 4 days
• Clarithromycin 7.5 mg/kg/dose PO BID (maximum = 250 mg/dose) x 10 days
• Clindamycin 7mg/kg/dose PO q8h x 10 days; Max: 300mg/dose
• Azithromycin Children ≥2 years and Adolescents: Oral: 12mg/kg/dose once daily for 5 days (maximum: 500mg daily)
• Amoxicillin 50mg/kg PO q24h x 10 days; Max: 1000mg/day
• Clarithromycin >6mo: 15mg/kg/day PO divided q12h x 7-10d
• Cephalexin 40mg/kg/day PO divided q12h x 10 days; Max: 500mg/dose
• Cefpodoxime 100mg q 12 h for 5-10 days
• Cefuroxime 250mg PO bid x10 days
• Cefuroxime 250mg PO bid x10 days