Permethrin: Difference between revisions
(Replace manual dosing with dynamic SMW tables) |
(Restore original dosing content alongside dynamic SMW tables) |
||
| Line 6: | Line 6: | ||
==Adult Dosing== | ==Adult Dosing== | ||
*Scabies: apply 5% cream head to toe, leave on 8-14 hrs prior to washing with soap/water. Repeat application in 14 days if living mites still present | |||
*Body/pubic lice: Apply 1% cream rinse to affected areas, then wash off after 10 minutes | |||
*Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Permethrin]] [[Has Population::Adult]] | {{#ask: [[Has DrugName::Permethrin]] [[Has Population::Adult]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | |||
*Scabies, >2mo: Apply cream head to toe,wash with soap/water after 8-14h. Repeat application if living mites present 14 days after initial treatment | |||
===Indications by Disease=== | ===Indications by Disease=== | ||
{{#ask: [[Has DrugName::Permethrin]] [[Has Population::Pediatric]] | {{#ask: [[Has DrugName::Permethrin]] [[Has Population::Pediatric]] | ||
|?Treats disease=Disease | |?Treats disease=Disease | ||
|?Has Dose=Dose | |?Has Dose=Dose | ||
|?Has Context=Context | |?Has Context=Context | ||
|format=table | |format=table | ||
|limit=50 | |limit=50 | ||
|mainlabel=- | |mainlabel=- | ||
|headers=show | |headers=show | ||
|sort=Treats disease | |sort=Treats disease | ||
}} | }} | ||
Latest revision as of 02:39, 20 March 2026
Administration
- Type: Pediculicide
- Dosage Forms: Cream or lotion
- Routes of Administration: Topical
- Common Trade Names: Nix, Elimite
Adult Dosing
- Scabies: apply 5% cream head to toe, leave on 8-14 hrs prior to washing with soap/water. Repeat application in 14 days if living mites still present
- Body/pubic lice: Apply 1% cream rinse to affected areas, then wash off after 10 minutes
- Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Scabies | 5% cream neck down leave 8-12hrs repeat 1-2wks | First line adults |
Pediatric Dosing
- Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment
- Scabies, >2mo: Apply cream head to toe,wash with soap/water after 8-14h. Repeat application if living mites present 14 days after initial treatment
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Scabies | 5% cream, apply head to toe (avoid mucous membranes), leave 8-12hrs, wash off; repeat in 1-2 weeks | Pediatric (>2 months) |
Special Populations
- Pregnancy Rating: B
- Lactation risk: Infant risk minimal
- Renal dosing: not defined
- Hepatic dosing: not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Serious reactions are rare
Common
- Rash, erythema, pruritus, burning/stinging sensation
- Swelling
Pharmacology
- Topical: <2% absorbed
- Half-life:
- Metabolism:
- Excretion: Renal
Mechanism of Action
- Disrupts neuronal sodium channel current in louse/mite, leading to delayed repolarization of nerve and subsequent paralysis/death