Template:Peritonitis Antibiotics: Difference between revisions

Revision as of 22:53, 19 March 2026

Intra-Abdominal Sepsis/Peritonitis

	Harbor-UCLA	Santa Monica-UCLA	Other
Primary	Metronidazole 500mg IV q8hrs Plus one of the following: Ceftriaxone 1g IV once daily Ciprofloxacin 400mg IV q12hrs Cefazolin 1g (30mg/kg) IV q8hrs Levofloxacin 750mg IV once daily	Metronidazole 500mg IV q8h + Vancomycin 15mg/kg/dose IV q12h (Max dose = 1500mg) Plus one of the following: Piperacillin/tazobactam 4.5g IV q6h Ertapenem 1g IV q24h Ceftriaxone 1g IV q24h	One of the following: Piperacillin-tazobactam Ticarcillin-clavulanate 3.1 g IV every 6 hours Ertapenem 1 g every 24 hours Moxifloxacin 400 mg IV every 24 hours
Allergy or prior exposure	Piperacillin/Tazobactam 4.5g (80mg/kg) IV q8hrs OR Metronidazole 500mg IV q8hrs PLUS Cefepime 2g IV once daily OR Ciprofloxacin 400mg IV q12hrs OR Levofloxacin 750mg IV once daily Meropenem 1g (20mg/kg) IV q8hrs OR Doripenem 500mg IV q8hrs OR Aztreonam 2g (30mg/kg) IV q8hrs + Metronidazole 500mg IV q8hrs	aztreonam 2g IV q8h + metronidazole 500mg IV q8h +/- vancomycin 15mg/kg/dose IV q12h (Max dose = 1500mg)

@@ Line 7: / Line 7: @@
 |-
 | Primary||
-*[[Metronidazole]] 500mg IV q8hrs
+*{{AntibioticDose|drug=Metronidazole|dose=500mg IV q8hrs|context=Primary}}
 *Plus one of the following:
-**[[Ceftriaxone]] 1g IV once daily
+**{{AntibioticDose|drug=Ceftriaxone|dose=1g IV once daily|context=Primary}}
-**[[Ciprofloxacin]] 400mg IV q12hrs
+**{{AntibioticDose|drug=Ciprofloxacin|dose=400mg IV q12hrs|context=Primary}}
-**[[Cefazolin]] 1g (30mg/kg) IV q8hrs
+**{{AntibioticDose|drug=Cefazolin|dose=1g (30mg/kg) IV q8hrs|context=Primary}}
-**[[Levofloxacin]] 750mg IV once daily
+**{{AntibioticDose|drug=Levofloxacin|dose=750mg IV once daily|context=Primary}}
 ||
 *[[Metronidazole]] 500mg IV q8h
 *+ [[Vancomycin]] 15mg/kg/dose IV q12h (Max dose = 1500mg)
 *Plus one of the following:
 **[[Piperacillin/tazobactam]] 4.5g IV q6h
 **[[Ertapenem]] 1g IV q24h
 **[[Ceftriaxone]] 1g IV q24h
 ||
 *One of the following:
 **[[Piperacillin-tazobactam]]
 **[[Ticarcillin-clavulanate]] 3.1 g IV every 6 hours
-**[[Ertapenem]] 1 g every 24 hours
+**{{AntibioticDose|drug=Ertapenem|dose=1 g every 24 hours|context=Primary}}
-**[[Moxifloxacin]] 400 mg IV every 24 hours
+**{{AntibioticDose|drug=Moxifloxacin|dose=400 mg IV every 24 hours|context=Primary}}
 |-
-| Allergy or prior exposure
+| Allergy or prior exposure ||
+*{{AntibioticDose|drug=Piperacillin/Tazobactam|dose=4.5g (80mg/kg) IV q8hrs|context=Allergy/Prior exposure}} OR
+*{{AntibioticDose|drug=Metronidazole|dose=500mg IV q8hrs|context=Allergy/Prior exposure}} PLUS
+**{{AntibioticDose|drug=Cefepime|dose=2g IV once daily|context=Allergy/Prior exposure}} OR
+**{{AntibioticDose|drug=Ciprofloxacin|dose=400mg IV q12hrs|context=Allergy/Prior exposure}} OR
+**{{AntibioticDose|drug=Levofloxacin|dose=750mg IV once daily|context=Allergy/Prior exposure}}
+*{{AntibioticDose|drug=Meropenem|dose=1g (20mg/kg) IV q8hrs|context=Allergy/Prior exposure}} OR
+*{{AntibioticDose|drug=Doripenem|dose=500mg IV q8hrs|context=Allergy/Prior exposure}} OR
+*{{AntibioticDose|drug=Aztreonam|dose=2g (30mg/kg) IV q8hrs|context=Allergy/Prior exposure}} + [[Metronidazole]] 500mg IV q8hrs
 ||
-*[[Piperacillin/Tazobactam]] 4.5g (80mg/kg) IV q8hrs OR
+*[[aztreonam]] 2g IV q8h
-*[[Metronidazole]] 500mg IV q8hrs PLUS
+*+ [[metronidazole]] 500mg IV q8h
-**[[Cefepime]] 2g IV once daily OR
-**[[Ciprofloxacin]] 400mg IV q12hrs OR
-**[[Levofloxacin]] 750mg IV once daily
-*[[Meropenem]] 1g (20mg/kg) IV q8hrs OR
-*[[Doripenem]] 500mg IV q8hrs OR
-*[[Aztreonam]] 2g (30mg/kg) IV q8hrs + [[Metronidazole]] 500mg IV q8hrs
-||
-*[[aztreonam]] 2g IV q8h
-*+ [[metronidazole]] 500mg IV q8h
 *+/- [[vancomycin]] 15mg/kg/dose IV q12h (Max dose = 1500mg)
 ||
 |}