Template:Periorbital Cellulitis Antibiotics: Difference between revisions

Revision as of 21:00, 19 March 2026

Antibiotics

Outpatient

Treatment recommended for 5-7 days. If signs of cellulitis persist at the end of this period, treatment should be continued until the eyelid erythema and swelling have resolved or nearly resolved.

TMP/SMX 1-2 double-strength tablets BID OR

- In children: TMP/SMX 8 to 12 mg/kg QD of the TMP component divided every 12 hours

Clindamycin 300mg Q8H - In children: Clindamycin 30 to 40 mg/kg per day in three to four equally divided doses, maximum 1.8 grams per day

PLUS one of the following agents:

Amoxicillin 875 mg BID OR

- In children: Amoxicillin 45-90 mg/kg per day divided every 12 hours

Cefpodoxime 400mg BID OR

- In children: Cefpodoxime 10 mg/kg per day divided every 12 hours, max 200 mg

Cefdinir 300 mg BID - In children: Cefdinir 14 mg/kg per day, divided every 12 hours, max daily 600 mg

Inpatient

Vancomycin 15-20mg/kg IV BID + (one of the following)
- Ampicillin/Sulbactam 3 g IV q6hr OR
- Ticarcillin/Clavulanate 3.1 g IV q4h OR
- Piperacillin/Tazobactam 4.5 g IV q6h OR
- Ceftriaxone 2 g IV q12hr OR
- Cefotaxime 2 g IV q4h

Pediatric:

Vancomycin 15mg/kg IV q6hrs + (one of the following)
- Ampicillin/Sulbactam 50mg/kg IV q6hrs (max 3g/dose) OR
- Piperacillin/Tazobactam 100mg/kg IV q8hrs (max 4.5g) OR
- Ceftriaxone 50mg/kg IV q12hrs (max 2g/dose) OR
- Cefotaxime 50mg/kg IV q6hrs (max 2g/dose)

@@ Line 1: / Line 1: @@
 ===Antibiotics===
 ====Outpatient====
 Treatment recommended for 5-7 days. If signs of cellulitis persist at the end of this period, treatment should be continued until the eyelid erythema and swelling have resolved or nearly resolved.
-*[[Trimethoprim-sulfamethoxazole]] 1-2 double-strength tablets BID '''OR'''
-- In children: 8 to 12 mg/kg QD of the TMP component divided every 12 hours
-*[[Clindamycin]] 300mg Q8H
-- In children: 30 to 40 mg/kg per day in three to four equally divided doses, maximum 1.8 grams per day
-'''PLUS one of the following agents:
-'''
-*[[Amoxicillin]] 875 mg BID '''OR'''
-- In children: usual dosing is 45 mg/kg per day divided every 12 hours; dosing for severe infections or when penicillin-resistant S. pneumoniae is a concern (using the 600 mg/5 mL suspension) is 90 mg/kg per day divided every 12 hours
-*[[Cefpodoxime]] 400mg BID '''OR'''
+*{{AntibioticDose|drug=TMP/SMX|dose=1-2 double-strength tablets BID|context=Outpatient}} '''OR'''
-- In children <12 years of age: 10 mg/kg per day divided every 12 hours, usual maximum dose 200 mg; in children ≥12 years and adolescents: 400 mg every 12 hours
+- In children: {{AntibioticDose|drug=TMP/SMX|dose=8 to 12 mg/kg QD of the TMP component divided every 12 hours|context=Outpatient|population=Pediatric}}
+*{{AntibioticDose|drug=Clindamycin|dose=300mg Q8H|context=Outpatient}} - In children: {{AntibioticDose|drug=Clindamycin|dose=30 to 40 mg/kg per day in three to four equally divided doses, maximum 1.8 grams per day|context=Outpatient|population=Pediatric}}
-*[[Cefdinir]] 300 mg BID
+'''PLUS one of the following agents: '''
-- In children: 14 mg/kg per day, divided every 12 hours, maximum daily dose 600 mg
+*{{AntibioticDose|drug=Amoxicillin|dose=875 mg BID|context=Outpatient}} '''OR'''
+- In children: {{AntibioticDose|drug=Amoxicillin|dose=45-90 mg/kg per day divided every 12 hours|context=Outpatient|population=Pediatric}}
+*{{AntibioticDose|drug=Cefpodoxime|dose=400mg BID|context=Outpatient}} '''OR'''
+- In children: {{AntibioticDose|drug=Cefpodoxime|dose=10 mg/kg per day divided every 12 hours, max 200 mg|context=Outpatient|population=Pediatric}}
+*{{AntibioticDose|drug=Cefdinir|dose=300 mg BID|context=Outpatient}} - In children: {{AntibioticDose|drug=Cefdinir|dose=14 mg/kg per day, divided every 12 hours, max daily 600 mg|context=Outpatient|population=Pediatric}}
 ====Inpatient====
 {{Orbital Cellulitis Antibiotics}}