Diphenhydramine: Difference between revisions
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*CNS depression | |||
*Anticholinergic sx | |||
===Common=== | ===Common=== | ||
*Sedation | |||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 18:11, 26 May 2015
General
- Type: Antihistamines H1 blocker
- Dosage Forms: Oral, IM, IV
- Common Trade Names: Benadryl
Adult Dosing
- Allergic Reaction
- Oral: 25-50 mg q4-8h, max 300 mg/day
- IM/IV: 10-50 mg/dose
- Parkinsonian symptoms
- Oral: 25-50 mg tid-qid
- IM/IV: 10-50 mg/dose
- Insomnia: 50 mg PO qhs
Pediatric Dosing
- Allergic Reaction
- Oral/IM/IV: 5 mg/kg/day divided q6-8h (1.25-1.67 mg/kg/dose)
- Alternate PO dosing
- 2-6 yo: 6.25 mg q4-6h
- 6-12 yo: 12-25 mg q4-6h
- >12 yo: Adult dosing
Special Populations
- Pregnancy Rating: Category B
- Lactation: Enters breast milk
- Renal Dosing: n/a
- Hepatic Dosing: n/a
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- CNS depression
- Anticholinergic sx
Common
- Sedation
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: