Template:Botulism treatment: Difference between revisions
| Line 15: | Line 15: | ||
**infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions | **infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions | ||
**Stop infusion after total of 100mg/kg infused | **Stop infusion after total of 100mg/kg infused | ||
*To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600 | *To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600<ref>http://www.infantbotulism.org/</ref> | ||
===Inhalational Botulism=== | ===Inhalational Botulism=== | ||
Revision as of 21:21, 24 May 2015
If suspect possible bioterrorism, contact CDC +1-770-488-7100
Supportive Care
- Early ventilatory support
- Consider intubation when vital capacity <30% predicted or <12cc/kg
- Wound Managment
- Early wound debreedment with surgical consult.
- Also exclude Necrotizing fasciitis and coverage with same broad antibiotic coverage
Foodborne Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through department of health / CDC. Hotline in LA: (888) 397-3993[1]
Infant Botulism (<1yo)
- Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
- infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions
- Stop infusion after total of 100mg/kg infused
- To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600[2]
Inhalational Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through dept of health / CDC. Hotline in LA: (888) 397-3993[1]
Wound Botulism
- Individualize therapy with ID consultant
- Broad antibiotic coverage same as for Necrotizing fasciitis while awaiting wound cultures