Endophthalmitis: Difference between revisions

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==Background==
==Background==
*Inflammation (usually infectious) of the deep eye structures (aqueous and vitreus chambers)
*Inflammation (usually infectious) of the deep eye structures (aqueous and vitreus chambers)
**Staphylococcus, Streptococcus, Bacillus cereus
**[[Staphylococcus]], [[Streptococcus]], [[Bacillus cereus]]
*Frequently leads to loss of vision (ocular emergency)
*Frequently leads to loss of vision (ocular emergency)


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*[[Globe Rupture]]
*[[Globe Rupture]]
**Penetrating eye trauma more at risk than blunt eye trauma
**Penetrating eye trauma more at risk than blunt eye trauma
*Foreign body
*[[Foreign body]]
*Extension of keratitis
*Extension of [[keratitis]]
*Hematogenous spread/endogenous (rare)
*Hematogenous spread/endogenous (rare)


==Clinical Features==
==Clinical Features==
#Headache
*[[Headache]]
#Eye pain
*[[Eye pain]]
#Photophobia
*Photophobia
#Vision loss
*[[Vision loss]]
#Ocular discharge
*Ocular discharge
#May also see:
*May also see:
##Conjunctival/scleral injection
**Conjunctival/scleral injection
##Chemosis
**Chemosis
##Hypopyon
**Hypopyon
##Uveitis
**Uveitis


==Differential Diagnosis==
==Differential Diagnosis==
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**After exclusion of [[Globe Rupture]]
**After exclusion of [[Globe Rupture]]
*Bloodwork (CBC, ESR, ) only if considering endogenous endophthalmitis
*Bloodwork (CBC, ESR, ) only if considering endogenous endophthalmitis
*Ultrasound to look for alternative diagnosis
*[[Ultrasound]] to look for alternative diagnosis
**After exclusion of [[Globe Rupture]]
**After exclusion of [[Globe Rupture]]


==Treatment==
==Treatment==
*Emergent ophtho consult (for gram stain/culture and definitive treatment of intravitreal abx)
*Emergent ophtho consult (for gram stain/culture and definitive treatment of intravitreal [[antibiotics]])
*Systemic antibiotics for endogenous endophthalmitis (rare cause)
*Systemic antibiotics for endogenous endophthalmitis (rare cause)
**Systemic antibiotics for other etiologies is controversial
**Systemic antibiotics for other etiologies is controversial

Revision as of 15:53, 20 May 2015

Endophthalmitis from retained foreign body

Background

Causes

  • Cataract surgery
    • Usually within 6 weeks
  • Globe Rupture
    • Penetrating eye trauma more at risk than blunt eye trauma
  • Foreign body
  • Extension of keratitis
  • Hematogenous spread/endogenous (rare)

Clinical Features

Differential Diagnosis

Diagnosis

  • Visual Acuity
  • Inspect of lid, cornea, sclera
  • Slit lamp exam
  • Intraocular pressure
  • Bloodwork (CBC, ESR, ) only if considering endogenous endophthalmitis
  • Ultrasound to look for alternative diagnosis

Treatment

  • Emergent ophtho consult (for gram stain/culture and definitive treatment of intravitreal antibiotics)
  • Systemic antibiotics for endogenous endophthalmitis (rare cause)
    • Systemic antibiotics for other etiologies is controversial
    • Antibiotic prophylaxis in Globe Rupture reduces incidence of endophthalmitis to <1%
    • tetanus, if indicated

Disposition

  • Admit

See Also

Eye Algorithm (Main) Globe Rupture

References