Template:Neisseria meningitis post exposure prophylaxis: Difference between revisions
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**125mg IM if ≤ 15 years old
**125mg IM if ≤ 15 years old
**Ceftriaxone should be used for pregnant patients
**Ceftriaxone should be used for pregnant patients
*[[Azithromycin]]
*[[Azithromycin]]<ref>https://www.cdph.ca.gov/Programs/OPA/Pages/CAHAN/ca-discontinuation-of-ciprofloxacin-for-invasive-meningococcal-disease-pep.aspx</ref>.
**Pediatric: 10 mg/kg (maximum 500 mg), po x 1
**Pediatric: 10 mg/kg (maximum 500 mg), po x 1
**Adult: 500 mg, po x 1
**Adult: 500 mg, po x 1

Revision as of 15:56, 6 November 2024

Only for meningococcus exposure

Indications

  • Household contacts
  • School or day care contacts in previous 7 days
  • Direct exposure to patient's secretions (kissing, shared utensils or toothbrush)
  • Intubation without facemark

Prophylaxis regimen

Either of the options are acceptable

  • Rifampin 600mg PO BID x2d
    • 5mg/kg PO if < 1 month old
    • 10mg/kg PO ≥ 1 month old
  • Ceftriaxone 250mg IM x1
    • 125mg IM if ≤ 15 years old
    • Ceftriaxone should be used for pregnant patients
  • Azithromycin[1].
    • Pediatric: 10 mg/kg (maximum 500 mg), po x 1
    • Adult: 500 mg, po x 1
  • Ciprofloxacin 500mg PO x1
    • No longer recommended as an option in California[2].
    • Do not use in patients with recent travel to Saudi Arabia[3]
  1. ↑ https://www.cdph.ca.gov/Programs/OPA/Pages/CAHAN/ca-discontinuation-of-ciprofloxacin-for-invasive-meningococcal-disease-pep.aspx
  2. ↑ https://www.cdph.ca.gov/Programs/OPA/Pages/CAHAN/ca-discontinuation-of-ciprofloxacin-for-invasive-meningococcal-disease-pep.aspx
  3. ↑ https://www.cdc.gov/mmwr/volumes/73/wr/mm7322e1.htm
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