Cocaine: Difference between revisions

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(Background, MOA, Picture)
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*[[Cocaine Intoxication]]
==Background==
*[[Cocaine Chest Pain]]
[[File:Kokain_-_Cocaine.svg.png |thumb|Cocaine chemical structure]]
*[[Cocaine Withdrawal]]
*A [[Sympathomimetic toxicity|sympathomimetic]] stimulant derived from an alkaloid paste made from the leaves of the coca plant
*[[Levamisole toxicity]]
*Both a legitimate medical drug and a drug of abuse
 
==Forms of Abuse==
*Cocaine can be smoked, snorted, injected or ingested
*Smoked form is often in a free-base or crack form
 
==Adverse effects==
*Acute
**Sympathomimetic qualities
***Tachycardia
***Fever
***Agitation
***Diaphoresis
*Chronic
**Atherosclerosis
**Cardiomyopathy
**Nasal Septum damage
**"Crack Lung"
 
==Mechanism of action==
*Blocks reuptake of serotonin, dopamine and norepinephrine
*Anesthetic effects achieved through sodium channel blockade


==Differential Diagnosis==
==Differential Diagnosis==
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==See Also==
==See Also==
*[[Sympathomimetic Toxicity]]
*[[Sympathomimetic Toxicity]]
*[[Cocaine Intoxication]]
*[[Cocaine Chest Pain]]
*[[Cocaine Withdrawal]]
*[[Levamisole toxicity]]


[[Category:Tox]]
[[Category:Tox]]
[[Category:Drugs]]
[[Category:Drugs]]

Revision as of 01:53, 24 April 2015

Background

Cocaine chemical structure
  • A sympathomimetic stimulant derived from an alkaloid paste made from the leaves of the coca plant
  • Both a legitimate medical drug and a drug of abuse

Forms of Abuse

  • Cocaine can be smoked, snorted, injected or ingested
  • Smoked form is often in a free-base or crack form

Adverse effects

  • Acute
    • Sympathomimetic qualities
      • Tachycardia
      • Fever
      • Agitation
      • Diaphoresis
  • Chronic
    • Atherosclerosis
    • Cardiomyopathy
    • Nasal Septum damage
    • "Crack Lung"

Mechanism of action

  • Blocks reuptake of serotonin, dopamine and norepinephrine
  • Anesthetic effects achieved through sodium channel blockade

Differential Diagnosis

Sympathomimetics

See Also