Cocaine: Difference between revisions
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==Background== | |||
*[[ | [[File:Kokain_-_Cocaine.svg.png |thumb|Cocaine chemical structure]] | ||
* | *A [[Sympathomimetic toxicity|sympathomimetic]] stimulant derived from an alkaloid paste made from the leaves of the coca plant | ||
* | *Both a legitimate medical drug and a drug of abuse | ||
==Forms of Abuse== | |||
*Cocaine can be smoked, snorted, injected or ingested | |||
*Smoked form is often in a free-base or crack form | |||
==Adverse effects== | |||
*Acute | |||
**Sympathomimetic qualities | |||
***Tachycardia | |||
***Fever | |||
***Agitation | |||
***Diaphoresis | |||
*Chronic | |||
**Atherosclerosis | |||
**Cardiomyopathy | |||
**Nasal Septum damage | |||
**"Crack Lung" | |||
==Mechanism of action== | |||
*Blocks reuptake of serotonin, dopamine and norepinephrine | |||
*Anesthetic effects achieved through sodium channel blockade | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
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==See Also== | ==See Also== | ||
*[[Sympathomimetic Toxicity]] | *[[Sympathomimetic Toxicity]] | ||
*[[Cocaine Intoxication]] | |||
*[[Cocaine Chest Pain]] | |||
*[[Cocaine Withdrawal]] | |||
*[[Levamisole toxicity]] | |||
[[Category:Tox]] | [[Category:Tox]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 01:53, 24 April 2015
Background
- A sympathomimetic stimulant derived from an alkaloid paste made from the leaves of the coca plant
- Both a legitimate medical drug and a drug of abuse
Forms of Abuse
- Cocaine can be smoked, snorted, injected or ingested
- Smoked form is often in a free-base or crack form
Adverse effects
- Acute
- Sympathomimetic qualities
- Tachycardia
- Fever
- Agitation
- Diaphoresis
- Sympathomimetic qualities
- Chronic
- Atherosclerosis
- Cardiomyopathy
- Nasal Septum damage
- "Crack Lung"
Mechanism of action
- Blocks reuptake of serotonin, dopamine and norepinephrine
- Anesthetic effects achieved through sodium channel blockade
Differential Diagnosis
Sympathomimetics
- Cocaine
- Amphetamines
- Synthetic cathinones (khat)
- Ketamine
- Ecstasy (MDMA)
- Synthetic cannabinoids
- Bath salts
