Emergency contraception: Difference between revisions

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==Treatment==
==Treatment==
===Progestin-Only Regimen===
===Progestin-Only Regimen===
# First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
*First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
##may take both at once
**may take both at once
# Relative risk reduction of pregnancy = 89% (1% with  vs 8% without)
*Relative risk reduction of pregnancy = 89% (1% with  vs 8% without)
# Side effects
*Side effects
## Nausea (23%)
**Nausea (23%)
## Vomiting (6%)
**Vomiting (6%)
#no teratogenisis
*No teratogenisis
# FDA approved regimens:
*FDA approved regimens:
## Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
**Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
***Plan B levonorgestrel 0.75mg po q12h x2


===Yuzpe Regimen===
===Yuzpe Regimen===
(combination OCPs)
(combination OCPs)
*Yuzpe ethinyl estradiol 100mcg po plus levonorgestral 0.5mg po; repeat in 12h


# First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
*First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
# May be given up to 120 hours later (but efficacy reduced)
*May be given up to 120 hours later (but efficacy reduced)
# Reduces risk of pregnancy by 75% (2% with vs 8% without)
*Reduces risk of pregnancy by 75% (2% with vs 8% without)
# Side effects
*Side effects
## Nausea (50%)
**Nausea (50%)
## Vomiting (20%)
**Vomiting (20%)
# Safety
*Safety
##  No teratogenic effect
**No teratogenic effect
# Contraindications
*Contraindications
## Pregnancy
** Pregnancy
# FDA approved regimens:
*FDA approved regimens:
## Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
** Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
## Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
** Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
## Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose
** Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose
## Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
** Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose


==Source==
==Source==
7/09 PANI


[[Category:OB/GYN]]
[[Category:OB/GYN]]

Revision as of 03:54, 15 January 2015

Treatment

Progestin-Only Regimen

  • First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
    • may take both at once
  • Relative risk reduction of pregnancy = 89% (1% with vs 8% without)
  • Side effects
    • Nausea (23%)
    • Vomiting (6%)
  • No teratogenisis
  • FDA approved regimens:
    • Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
      • Plan B levonorgestrel 0.75mg po q12h x2

Yuzpe Regimen

(combination OCPs)

  • Yuzpe ethinyl estradiol 100mcg po plus levonorgestral 0.5mg po; repeat in 12h
  • First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
  • May be given up to 120 hours later (but efficacy reduced)
  • Reduces risk of pregnancy by 75% (2% with vs 8% without)
  • Side effects
    • Nausea (50%)
    • Vomiting (20%)
  • Safety
    • No teratogenic effect
  • Contraindications
    • Pregnancy
  • FDA approved regimens:
    • Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
    • Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
    • Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose
    • Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose

Source