Dobutamine: Difference between revisions
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===Indication=== | |||
*Cardiogenic shock | |||
*Low-output heart failure | |||
*Tricyclic overdose | |||
===Primary Receptor=== | |||
* β1 | |||
* β2 | |||
===Relative Effects=== | |||
*↑↑↑SV | |||
*↑↑HR | |||
*↓SVR (transient, from β2 agonism) | |||
===Dosing=== | |||
*2-20mcg/kg/min | |||
**10mcg works for most | |||
*May use in peripheral IV | |||
===Rate of Titration=== | |||
*Q2-5 min | |||
===Adverse Effects=== | |||
*Tachyarrhythmias | |||
*Myocardial ischemia | |||
*Hypotension as β2 effect may result in vasodilation | |||
**Caution if SBP <90 | |||
Revision as of 14:10, 20 December 2014
General
- Type: Vasopressors
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
Indication
- Cardiogenic shock
- Low-output heart failure
- Tricyclic overdose
Primary Receptor
- β1
- β2
Relative Effects
- ↑↑↑SV
- ↑↑HR
- ↓SVR (transient, from β2 agonism)
Dosing
- 2-20mcg/kg/min
- 10mcg works for most
- May use in peripheral IV
Rate of Titration
- Q2-5 min
Adverse Effects
- Tachyarrhythmias
- Myocardial ischemia
- Hypotension as β2 effect may result in vasodilation
- Caution if SBP <90