Portal vein thrombosis

Background

Inciting Causes

• Abdominal sepsis
• Abdominal surgery

Behçet's syndrome Cirrhosis Collagen vascular diseases (eg, lupus) Compression or invasion of the portal vein by tumor (eg, pancreatic cancer) Endoscopic sclerotherapy Hepatocellular carcinoma Inflammatory bowel disease Inherited thrombophilias Myeloproliferative syndromes Omphalitis Oral contraceptives Pancreatic islet cell transplantation Pancreatitis Paroxysmal nocturnal hemoglobinuria Pregnancy Retroperitoneal fibrosis Transjugular intrahepatic portosystemic shunt Trauma

Clinical Features

Acute

• Abdominal pain developing suddenly or progressing over a few days
• May be clinically silent in a portion of patients and diagnosed during a CT exam for other reasons (e.g. acute pancreatitis)

Evaluation

• Typically diagnosed on abdominal CT with contrast