Penicillin G Procaine: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===[[Anthrax]]=== | |||
*Inhalational (Postexposure Prophylaxis) | |||
**1,200,000 units IM q12 hours x 60 days (see below) | |||
**Info: Total treatment duration = 60 days. Do not give IM for over 2 weeks, switching alternative treatment to complete course | |||
*Cutaneous, Nonsevere (Treatment) | |||
**600,000-1,200,000 units/day IM | |||
===[[Endocarditis]] by susceptible [[Streptococcus viridans]]=== | |||
*1.2 million units IM q6 hours x 2-4 weeks + [[aminoglycoside]] | |||
===Neurosyphilis=== | |||
*2.4 million units/day IM + 500 mg probenecid PO QID x 10-14 days | |||
*Info: [[Penicillin G]] aqueous I.V. is preferred | |||
===Whipple's Disease=== | |||
*1.2 million units/day + streptomycin x 10-14 days | |||
*Followed by [[trimethoprim/sulfamethoxazole]] or doxycycline x 1 year | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 21:08, 6 April 2014
General
- Type: Natural Penicillin
- Dosage Forms: IM
- Common Trade Names:
Adult Dosing
Anthrax
- Inhalational (Postexposure Prophylaxis)
- 1,200,000 units IM q12 hours x 60 days (see below)
- Info: Total treatment duration = 60 days. Do not give IM for over 2 weeks, switching alternative treatment to complete course
- Cutaneous, Nonsevere (Treatment)
- 600,000-1,200,000 units/day IM
Endocarditis by susceptible Streptococcus viridans
- 1.2 million units IM q6 hours x 2-4 weeks + aminoglycoside
Neurosyphilis
- 2.4 million units/day IM + 500 mg probenecid PO QID x 10-14 days
- Info: Penicillin G aqueous I.V. is preferred
Whipple's Disease
- 1.2 million units/day + streptomycin x 10-14 days
- Followed by trimethoprim/sulfamethoxazole or doxycycline x 1 year
Pediatric Dosing
Special Populations
- Pregnancy:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: