EBQ:MATTERs Study: Difference between revisions

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| fulltexturl= http://archsurg.jamanetwork.com/article.aspx?articleid=1107351
| fulltexturl= http://archsurg.jamanetwork.com/article.aspx?articleid=1107351
| pdfurl= http://archsurg.jamanetwork.com/data/Journals/SURG/22581/siz110024_113_119.pdf
| pdfurl= http://archsurg.jamanetwork.com/data/Journals/SURG/22581/siz110024_113_119.pdf
| status = Under Review
}}
}}



Revision as of 10:40, 10 March 2014

Under Review Journal Club Article
Morrison J. et al. "Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study". JAMA Surgery. 2012. 147(2):113-119.
PubMed Full text PDF

Clinical Question

Does administration of Tranexamic (TXA) acid in trauma patients with hemorrhage improve mortality in a wartime setting?

Conclusion

The use of TXA with blood component-based resuscitation following combat injury results in improved measures of coagulopathy and survival, a benefit that is most prominent in patients requiring massive transfusion

Major Points

Inclusion Criteria

Exclusion Criteria

Interventions

Outcome

Primary Outcomes

Secondary Outcomes

Subgroup analysis

Criticisms

Funding

Sources