Metronidazole: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===General=== | ===General=== | ||
*PO | *'''PO''' | ||
**500 mg PO q6-8h x 7-10 days | **500 mg PO q6-8h x 7-10 days | ||
**First Dose: 500 mg PO x 1 | **First Dose: 500 mg PO x 1 | ||
*IV | *'''IV''' | ||
**15mg/kg IV x1, then 7.5mg/kg IV q6h | **15mg/kg IV x1, then 7.5mg/kg IV q6h | ||
**First Dose: 15mg/kg IV x1 | **First Dose: 15mg/kg IV x1 | ||
| Line 22: | Line 22: | ||
===General (>1200g AND <1 Month Old)=== | ===General (>1200g AND <1 Month Old)=== | ||
*<7 days old | *'''<7 days old''' | ||
**7.5-15 mg/kg/day PO/IV q12-24h | **7.5-15 mg/kg/day PO/IV q12-24h | ||
**First Dose: 7.5-15 mg/kg PO/IV x 1 | **First Dose: 7.5-15 mg/kg PO/IV x 1 | ||
*>7 days old | *'''>7 days old''' | ||
**15-30 mg/kg/day PO/IV q12h | **15-30 mg/kg/day PO/IV q12h | ||
**First Dose: 7.5-15 mg/kg PO/IV x 1 | **First Dose: 7.5-15 mg/kg PO/IV x 1 | ||
| Line 35: | Line 35: | ||
==Special Populations== | ==Special Populations== | ||
*Pregnancy: | *Pregnancy: B | ||
*Lactation: | *Lactation: Safety conditional | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult | ||
Revision as of 22:53, 3 March 2014
General
- Type: Other Antibacterials
- Dosage Forms:
- IV
- PO: 250mg; 375mg; 500mg
- Common Trade Names: Flagyl
Adult Dosing
General
- PO
- 500 mg PO q6-8h x 7-10 days
- First Dose: 500 mg PO x 1
- IV
- 15mg/kg IV x1, then 7.5mg/kg IV q6h
- First Dose: 15mg/kg IV x1
- Max: 1 gram/dose
Pediatric Dosing
General (<1200g)
- 7.5 mg/kg PO/IV q48h
- First Dose: 7.5 mg/kg PO/IV x 1
General (>1200g AND <1 Month Old)
- <7 days old
- 7.5-15 mg/kg/day PO/IV q12-24h
- First Dose: 7.5-15 mg/kg PO/IV x 1
- >7 days old
- 15-30 mg/kg/day PO/IV q12h
- First Dose: 7.5-15 mg/kg PO/IV x 1
General (>1 Month Old)
- 30 mg/kg/day PO/IV q6h
- First Dose: 7.5 mg/kg PO/IV x 1
- Max: 4 g/day
Special Populations
- Pregnancy: B
- Lactation: Safety conditional
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Source
- Epocrates