Cefazolin: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===General=== | ===General=== | ||
500-1000 mg IM/IV q6-8h | *Mild: 250-500 mg IM/IV 8h | ||
*Mod-Severe: 500-1000 mg IM/IV q6-8h | |||
*Life Threatening: 1-1.5g IM/IV q6h | |||
*Max: 12g/day | |||
===[[UTI]], Uncomplicated=== | |||
*1g IM/IV q12 | |||
===Pneumococcal [[Pneumonia]]=== | |||
*500mg IM/IV q12 | |||
===[[Endocarditis]] Prophylaxis, Dental=== | |||
*1g IM/IV x1 (30-60 min before procedure) | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 22:29, 27 February 2014
General
- Type: 1st gen Cephalosporin
- Dosage Forms: IV, IM
- Common Trade Names: Ancef
Adult Dosing
General
- Mild: 250-500 mg IM/IV 8h
- Mod-Severe: 500-1000 mg IM/IV q6-8h
- Life Threatening: 1-1.5g IM/IV q6h
- Max: 12g/day
UTI, Uncomplicated
- 1g IM/IV q12
Pneumococcal Pneumonia
- 500mg IM/IV q12
Endocarditis Prophylaxis, Dental
- 1g IM/IV x1 (30-60 min before procedure)
Pediatric Dosing
Special Populations
- Pregnancy: B
- Lactation: Safe
- Renal
- Hepatic
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 1.8h (3.7 ESRD)
- Metabolism: other; CYP450
- Excretion: Urine
- Mechanism of Action: Bactericidal; inhibits cell wall mucopeptide synthesis
See Also
Source
- Epocrates