CHF medications: Difference between revisions
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==Target Doses== | ==Target Doses== | ||
*Hydralazine: 100 TID start 25 | *[[Hydralazine]]: 100 TID start 25 | ||
*Isordil: 60-80 TID | *Isordil: 60-80 TID | ||
*Captopril: 100 TID start 12.5 | *[[Captopril]]: 100 TID start 12.5 | ||
*Lisinopril/enalapril: 10 bid class II/III | *[[Lisinopril]]/[[enalapril]]: 10 bid class II/III | ||
**20 bid class IV | **20 bid class IV | ||
*Carvedilol 25 BID; 50 BID if >80kg | *[[Carvedilol]] 25 BID; 50 BID if >80kg | ||
*Digoxin: varies | *[[Digoxin]]: varies | ||
*Spironolactone 25-50 qd | *[[Spironolactone]] 25-50 qd | ||
*Enalapril 1.25mg IV | *[[Enalapril]] 1.25mg IV | ||
*Nitroglycerin (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 10-200ug/min) | *[[Nitroglycerin]] (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 10-200ug/min) | ||
*Nitroprusside (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 5-400ug/min) | *[[Nitroprusside]] (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 5-400ug/min) | ||
^Consider when need afterload reduction | ^Consider when need afterload reduction | ||
Revision as of 00:41, 20 March 2017
| Agent | RA | RCW | SVR | BP | CO |
| Isordil 60 | - | - | (-) | - | -/+ |
| Hydralazine 100 | ~ | ~ | - | +/- | ++ |
| hy (MR/AI) | - | -- | ++ | -/+ | +/- |
| ACEI | - | - | - | +/- | + |
| Minoxidil | ~ | ~ | -- | +/- | ++ |
- Carvedilol: decreases mortality 67%
- Digoxin: decrease syx/hospitaliz
- Aldactone in Class IV decrease mortality
- Isordil: cor. VD; +BP if ischemia
- ISDN/HYDRA. decreased mortality in CHF
- ACEI GREAT mortality benefit
Target Doses
- Hydralazine: 100 TID start 25
- Isordil: 60-80 TID
- Captopril: 100 TID start 12.5
- Lisinopril/enalapril: 10 bid class II/III
- 20 bid class IV
- Carvedilol 25 BID; 50 BID if >80kg
- Digoxin: varies
- Spironolactone 25-50 qd
- Enalapril 1.25mg IV
- Nitroglycerin (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 10-200ug/min)
- Nitroprusside (Initial dose 5-10ug/min, increased every 3-5 minute to dose range 5-400ug/min)
^Consider when need afterload reduction