Nephrogenic Systemic Fibrosis: Difference between revisions

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#REDIRECT[[Nephrogenic systemic fibrosis]]
==Background==
*Rare but serious scleroderma-like condition associated with gadolinium (MRI contrast) exposure in patients with renal impairment
*Risk of nephrogenic systemic fibrosis (NSF) with any renal impairment, acute or chronic, does not have to have ESRD
 
==Clinical Features==
*Develops days to years after gadolinium exposure
*Chronic, progressive
*Skin becomes tight, thick, shiny, and indurated skin, with fibrotic nodules and plaques and brawny hyperpigmentation
**Painful, pruritic
**Extremities most commonly affected, followed by trunk. Face rarely involved
*Flexion contractures when lesions overlie joints, limited range of motion
*Neuromuscular involvement can occur
*In most severe cases, fibrosis involves internal organs (heart, lungs, liver)
 
==Differential Diagnosis==
 
==Evaluation==
 
==Management==
*No specific management, supportive care
 
==Disposition==
*Discharge
 
==See Also==
*[[MRI contraindications]]
==External Links==
 
==References==
<references/>
 
[[Category:Renal]] [[Category:Radiology]]

Latest revision as of 06:19, 24 September 2016