Isoproterenol: Difference between revisions
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==Pediatric Dosing== | ==Pediatric Dosing== | ||
*No well controlled studies for appropriate dosing | *No well controlled studies for appropriate dosing | ||
*AHA recommends initial infusion of 0.1 mcg/kg/min, with titrated range usually 0.1-1 mcg/kg/min | *AHA recommends initial infusion of 0.1 mcg/kg/min, with titrated range usually 0.1-1 mcg/kg/min<ref>GlobalRPH. Isoproterenol Dilution. http://www.globalrph.com/isoproterenol_dilution.htm.</ref> | ||
==Special Populations== | ==Special Populations== | ||
Revision as of 21:07, 5 August 2016
General
- Type: Beta agonist; Antiarrhythmics
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Loading dose: 0.02-0.06 mg IV, followed by infusion[1][2]
- 2-20 mcg/min IV infusion
- Titrate to HR and BP
Pediatric Dosing
- No well controlled studies for appropriate dosing
- AHA recommends initial infusion of 0.1 mcg/kg/min, with titrated range usually 0.1-1 mcg/kg/min[3]
Special Populations
- Pregnancy Rating:
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- Refractory torsades
- Refractory symptomatic bradycardia
Contraindications
- Allergy to class/drug
Adverse Reactions
- Dramatic increase in O2 demand
- V-tach (use lowest dose possible)
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Kinetics
- Onset of action = 1-5min
- Duration of action = 1-2hr
Comments
See Also
References
- ↑ GlobalRPH. Isoproterenol Dilution. http://www.globalrph.com/isoproterenol_dilution.htm.
- ↑ AthenaHealth. Epocrates. Isoproterenol - Entire Monograph. https://online.epocrates.com/u/10a106/isoproterenol.
- ↑ GlobalRPH. Isoproterenol Dilution. http://www.globalrph.com/isoproterenol_dilution.htm.