Brugada syndrome: Difference between revisions

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==Pathophysiology==
==Pathophysiology==
*Genetically-linked Na channelopathy
**Incomplete RBBB with ST elevation in V1-V3
**Increased risk of sudden cardiac death
***~10%/yr
**Much more common in men (up to 9x)
==ECG Criteria==
*Note - ECG findings can be TRANSIENT


Genetically-linked sodium channelopathy, characterized by incomplete RBBB with ST elevation in V1 and V2, and an increased risk of sudden cardiac death


Note - EKG findings can be TRANSIENT
*Type 1-Elevated ST segment (>2mm) descends w/ upward convexity to a TWI
 
*Type 2-Elevated ST segment (>1mm) descends toward baseline then rises again (saddleback) to upright T wave
==EKG Criteria==
*Type 3-Elevated ST segment (<1mm) descends toward baseline then rises again to upright T wave  
 
*Type 1 - 2 mm J-point elevation a gradually descending ST segment and a negative T-wave
*Type 2 - saddle back pattern with at least 2 mm J-point elevation and at least 1 mm ST elevation with a positive or biphasic T-wave
*Type 3 - saddle back pattern with less than 2 mm J-point elevation and less than 1 mm ST elevation with a positive T-wave


==Disposition==
==Disposition==
*a/w polymorphic v tach, v fib.
*Pts need an AICD
*mortality ~10% / yr
*pts need an AICD


==Source==
==Source==
Adapted from ....Mattu (lecture)
UpToDate


[[Category:Cards]]
[[Category:Cards]]

Revision as of 00:15, 27 April 2011

Pathophysiology

  • Genetically-linked Na channelopathy
    • Incomplete RBBB with ST elevation in V1-V3
    • Increased risk of sudden cardiac death
      • ~10%/yr
    • Much more common in men (up to 9x)

ECG Criteria

  • Note - ECG findings can be TRANSIENT


  • Type 1-Elevated ST segment (>2mm) descends w/ upward convexity to a TWI
  • Type 2-Elevated ST segment (>1mm) descends toward baseline then rises again (saddleback) to upright T wave
  • Type 3-Elevated ST segment (<1mm) descends toward baseline then rises again to upright T wave

Disposition

  • Pts need an AICD

Source

UpToDate