Neutropenia: Difference between revisions

(Created page with "==Background== {{Neutropenia background}} ==See Also== *Neutropenic fever Category:Heme/Onc")
 
Line 1: Line 1:
==Background==
==Background==
{{Neutropenia background}}
{{Neutropenia background}}
{{Neutropenic fever definition}}


==See Also==
==See Also==

Revision as of 03:22, 3 August 2016

Background

Neutropenia

  • ANC = (total WBC) x (%segs + %bands)
  • Nadir usually occurs 5-10 days after chemotherapy
  • Duration of neutropenia depends on type of cancer treatment
    • Solid tumor treatments: <5 days
    • Hematologic malignancies: 14 days or longer

Neutropenic fever definition

  • ANC <500 OR <1000 with predicted nadir of <500 in 48h AND
  • Fever ≥ 38.3˚C (100.9˚F) once OR sustained temperature ≥38 (100.4) for >1hr
    • Oral temperature (do not obtain rectal temp; risk of inducing bacteremia[1])

See Also

  1. Fleischman RJ. Emergency Complications of Malignancy. In: Cydulka RK, Fitch MT, Joing SA, Wang VJ, Cline DM, Ma O. eds. Tintinalli's Emergency Medicine Manual, 8e. McGraw-Hill; Accessed December 09, 2020. https://accessemergencymedicine.mhmedical.com/content.aspx?bookid=2158&sectionid=162273381