Docusate: Difference between revisions
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*Hepatotoxicity (Rare) | *Hepatotoxicity (Rare) | ||
===Common=== | ===Common=== | ||
*Diarrhea, nausea, cramping | *[[Diarrhea]], nausea, cramping | ||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: | ||
Revision as of 16:11, 24 September 2016
Administration
- Type: stool softener; laxitive
- Dosage Forms:
- Routes of Administration: Oral, rectal
- Common Trade Names: Colace
Adult Dosing
- 50 to 200mg daily or in 2-4 divided doses
Pediatric Dosing
- <3y: 10 to 40mg/day in 1-4 divided doses
- 3-6y: 20 to 60mg/day in 1-4 divided doses
- 6-12y: 40 to 120mg/day in 1-4 divided doses
Special Populations
- Pregnancy Rating: A
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Acute obstruction
- Acute abdominal pain, vomiting
- concurrent use of mineral oil
Adverse Reactions
Serious
- Hepatotoxicity (Rare)
Common
- Diarrhea, nausea, cramping
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Draws water into stool