Osmolal or Osmolar Gap: Difference between revisions

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#Sugar
#Sugar
##Glycerol
##Glycerol
##Manitol
##[[Mannitol]]
#Ketones
#Ketones
##Acetone
##Acetone

Revision as of 17:57, 16 March 2015

Definitions

  • Osmolarity = the total number of particles in solution per liter
  • Osmolality = the number of particles per kilogram of solvent

Calculations

Calculated Osm

Calculated Osm = 2 x Na + (glu/18) + (BUN/2.8) + (ethanol/4.6) + (methanol/2.6) + (ethylene glycol/5) + (acetone/5.5) + (isopropanol/5.9)

  • Normal = 275-295

Osmolal Gap

  • Osmolal Gap = measured osm - calculated osm
    • Normal = (-)14-10 mOsm/L

DDX

  1. Alcohols
    1. Methanol
    2. Ethylene glycol
    3. Isopropyl
  2. Sugar
    1. Glycerol
    2. Mannitol
  3. Ketones
    1. Acetone

See Also