Oxcarbazepine: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===Partial seizures=== | |||
*adjunct tx: Dose: 600 mg PO bid; Start: 300 mg PO bid, incr. by up to 600 mg/day qwk; Max: 2400 mg/day; | |||
*conversion to monotherapy: Dose: 1200 mg PO bid; Start: 300 mg PO bid, incr. by up to 600 mg/day qwk; Max: 2400 mg/day; D/C concomitant anticonvulsants over 3-6wk; taper dose gradually to D/C | |||
*initial monotherapy: Dose: 600 mg PO bid; Start: 300 mg PO bid, incr. by 300 mg/day q3 days; Max: 2400 mg/day | |||
===Trigeminal neuralgia=== | |||
*450-1200 mg PO bid | |||
*Start: 300 mg PO bid, may incr. by 600 mg/day qwk | |||
===Bipolar disorder=== | |||
*600-1200 mg PO bid | |||
*Start: 300 mg PO bid, incr. by 300 mg/day q3 days or by 600 mg/day qwk | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 23:23, 10 February 2016
Administration
- Type: anti epileptic
- Dosage Forms: 150,300,600; 300/5 mL
- Routes of Administration: PO
- Common Trade Names: Trileptal
Adult Dosing
Partial seizures
- adjunct tx: Dose: 600 mg PO bid; Start: 300 mg PO bid, incr. by up to 600 mg/day qwk; Max: 2400 mg/day;
- conversion to monotherapy: Dose: 1200 mg PO bid; Start: 300 mg PO bid, incr. by up to 600 mg/day qwk; Max: 2400 mg/day; D/C concomitant anticonvulsants over 3-6wk; taper dose gradually to D/C
- initial monotherapy: Dose: 600 mg PO bid; Start: 300 mg PO bid, incr. by 300 mg/day q3 days; Max: 2400 mg/day
Trigeminal neuralgia
- 450-1200 mg PO bid
- Start: 300 mg PO bid, may incr. by 600 mg/day qwk
Bipolar disorder
- 600-1200 mg PO bid
- Start: 300 mg PO bid, incr. by 300 mg/day q3 days or by 600 mg/day qwk
Pediatric Dosing
Special Populations
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: