Thyroid disease (main)

Background

Spectrum of Disease

Hypo <--> Hyper

myxedema coma << hypothyroid < euthyroid < hyperthyroid << thyroid storm

Other

1. cretinism- no congenital t3/t4
2. parafollicular C cells make calcitonin to keep the bone in
3. endemic goiter- if pt from area c low iodine I intake
4. free t3 & t4 determines thyroid state- not total plasma conc
5. t4-> t3 active & rt3 inactive
6. trh -> tsh -> t4 ->t3. t3 I's pittry
7. hthal pitutry gland
8. thyroid state changes dtr relax and contract speed and bmr O2 use.

See Also

Thyroid Storm

Endo: Hyperthyroidism

Endo: Myxedema Coma

Endo: Hypothyroidism