EBQ:Paramedic Trial: Difference between revisions
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===Exclusion Criteria=== | ===Exclusion Criteria=== | ||
*Cardiac arrest caused by trauma | |||
*Known or apparent pregnancy | |||
==Interventions== | ==Interventions== | ||
Revision as of 22:36, 7 August 2015
Under Review Journal Club Article
Perkins GD. et al.. "Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial". Lancet. 2015. 385(9972):947-55.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Does prehospital LUCAS-2 mechanical CPR improve survival from out-of-hospital cardiac arrest?
Conclusion
The use of LUCAS-2 in non-traumatic, out-of-hospital cardiac arrests did not show improvement over manual CPR in patient survival to 30 days.
Major Points
- Survival to 30 days had no difference with 6% (LUCAS-2) vs. 7% (control)
- No difference in ROSC, survival of event, survival to 3 months, or survival to 12 months
- Decreased favorable neurologic outcome (CPC 1 or 2) in LUCAS-2 group
Study Design
Pragmatic, cluster randomized, controlled trial
Population
91 ambulance stations (selected for being urban and semi-urban) from 4 UK National Health Service (NHS) Ambulance Services (West Midlands, North East England, Wales, South Central).
Patient Demographics
Inclusion Criteria
Exclusion Criteria
- Cardiac arrest caused by trauma
- Known or apparent pregnancy