Potassium iodide: Difference between revisions
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Latest revision as of 21:58, 20 March 2026
Administration
- Type: Antidote, antithyroid agent
- Dosage Forms:
- Routes of Administration: Oral
- Common Names: SSKI
Adult Dosing
- Post radiation exposure, thyroid injury prophylaxis: 130mg PO daily
- Induction of thyroid involution: 60-250mg PO TID for 10d prior to surgery
Pediatric Dosing
- Post radiation exposure, thyroid injury prophylaxis:
- <1mo: 16.25mg PO daily
- 1mo-3y: 32.5mg PO daily
- 3-12y: 65mg PO daily
- >12yo, <68kg: 65mg PO daily
- >12yo, >68kg: 130mg PO daily
Special Populations
- Pregnancy Rating: D
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing: avoid
- Hepatic dosing:
Contraindications
- Allergy to class/drug
- Renal disorders
- Iodide-induced goiter
Adverse Reactions
Serious
- Goiter, hypothyroidism, thyroid adenoma
- Hypersensitivity reaction
Common
- Rash
- GI irritation
- Paresthesia
Pharmacology
- Half-life:
- Metabolism:
- Excretion: Renal
Mechanism of Action
- Protects the thyroid gland by blocking the uptake of radioactive isotopes of iodine
Comments
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Thyroid storm | 5 drops (250 mg) PO q6h (give 1 hour after PTU/methimazole) | Block hormone release (Wolff-Chaikoff effect) | PO | Adult |