Cocaine: Difference between revisions
(Background, MOA, Picture) |
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*Both a legitimate medical drug and a drug of abuse | *Both a legitimate medical drug and a drug of abuse | ||
==Forms of Abuse== | ===Forms of Abuse=== | ||
*Cocaine can be smoked, snorted, injected or ingested | *Cocaine can be smoked, snorted, injected or ingested | ||
*Smoked form is often in a free-base or crack form | *Smoked form is often in a free-base or crack form | ||
Revision as of 20:25, 4 June 2015
Background
- A sympathomimetic stimulant derived from an alkaloid paste made from the leaves of the coca plant
- Both a legitimate medical drug and a drug of abuse
Forms of Abuse
- Cocaine can be smoked, snorted, injected or ingested
- Smoked form is often in a free-base or crack form
Adverse effects
- Acute
- Sympathomimetic qualities
- Tachycardia
- Fever
- Agitation
- Diaphoresis
- Sympathomimetic qualities
- Chronic
- Atherosclerosis
- Cardiomyopathy
- Nasal Septum damage
- "Crack Lung"
Mechanism of action
- Blocks reuptake of serotonin, dopamine and norepinephrine
- Anesthetic effects achieved through sodium channel blockade
Differential Diagnosis
Sympathomimetics
- Cocaine
- Amphetamines
- Synthetic cathinones (khat)
- Ketamine
- Ecstasy (MDMA)
- Synthetic cannabinoids
- Bath salts