Packed red blood cells: Difference between revisions
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*Can give type O Rh-positive pRBCs to a man or woman no longer of child-bearing age | *Can give type O Rh-positive pRBCs to a man or woman no longer of child-bearing age | ||
*Options: | *Options: | ||
**Leukocyte reduced | |||
***Eliminates 70-85% of leukocytes | |||
***Reduces nonhemolytic febrile reactions | |||
***Prevents sensitization in pts who may require bone marrow transplant | |||
***Minimizes risk of HIV and CMV infection | |||
**Irradiated | |||
***Eliminates capacity of T-cells to proliferate (prevents graft-versus-host disease) | |||
***Consider in transplant pts, neonates and immunocompromised patients | |||
**Washed | |||
***Indicated for pts w/ hypersensitivity to plasma (such as IgA deficiency) | |||
==Indications== | ==Indications== | ||
Revision as of 17:35, 5 April 2015
Features
- Can give type O Rh-positive pRBCs to a man or woman no longer of child-bearing age
- Options:
- Leukocyte reduced
- Eliminates 70-85% of leukocytes
- Reduces nonhemolytic febrile reactions
- Prevents sensitization in pts who may require bone marrow transplant
- Minimizes risk of HIV and CMV infection
- Irradiated
- Eliminates capacity of T-cells to proliferate (prevents graft-versus-host disease)
- Consider in transplant pts, neonates and immunocompromised patients
- Washed
- Indicated for pts w/ hypersensitivity to plasma (such as IgA deficiency)
- Leukocyte reduced
Indications
- Acute hemorrhage or chronic anemia with Hb <6
- Symptomatic anemia or cardiopulmonary disease AND Hb <10
Dose
- One unit (250mL) raises hemoglobin by 1 g/dl
- Usually transfuse at least 2 units at a time (15mL/kg in peds)
- Must transfuse no slower than 1 unit/4hr
- If require slower transfusion (e.g. risk for volume overload) the pRBC can be split
See Also
Source
Tintinalli