Succinylcholine: Difference between revisions
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==General== | ==General== | ||
*Type: [[Neuromuscular blocker]] | *Type: [[Neuromuscular blocker]] | ||
*Dosage Forms: | *Dosage Forms: IV or IM | ||
*Common Trade Names: | *Common Trade Names: | ||
==Adult Dosing== | ==Adult Dosing== | ||
*1.5 mg/kg IV | |||
*4 mg/kg IM (in extremis) | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Fatal hyperkalemia | |||
*Malignant hyperthermia | |||
*Masseter spasm | |||
===Common=== | ===Common=== | ||
==Pharmacology== | ==Pharmacology== | ||
* | *Onset: 45-60 seconds | ||
*Metabolism: | *Metabolism: | ||
*Excretion: | *Excretion: | ||
*Mechanism of Action: | *Mechanism of Action: | ||
*Duration of Action: 5-10 minutes | |||
==See Also== | ==See Also== | ||
Revision as of 23:19, 18 September 2015
See critical care quick reference for drug doses by weight.
General
- Type: Neuromuscular blocker
- Dosage Forms: IV or IM
- Common Trade Names:
Adult Dosing
- 1.5 mg/kg IV
- 4 mg/kg IM (in extremis)
Pediatric Dosing
See critical care quick reference for drug doses by weight.
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Hyperkalemia
- Preexisting hyperkalemia
- Burns >5d old
- Crush injury >5d old
- Severe infection >5d old
- Neuromuscular diseases (e.g. Myasthenia Gravis), myopathies
- History of Malignant Hyperthermia
- Allergy to class/drug
Adverse Reactions
Serious
- Fatal hyperkalemia
- Malignant hyperthermia
- Masseter spasm
Common
Pharmacology
- Onset: 45-60 seconds
- Metabolism:
- Excretion:
- Mechanism of Action:
- Duration of Action: 5-10 minutes
See Also
Sources
- Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis.