Dimenhydrinate: Difference between revisions
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*Dosage Forms: | *Dosage Forms: | ||
*Routes of Administration: oral, IV/IM | *Routes of Administration: oral, IV/IM | ||
*Common Trade Names: | *Common Trade Names: Dramamine | ||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 22:25, 7 March 2021
Administration
- Type: Antiemetics; Antihistamines
- Dosage Forms:
- Routes of Administration: oral, IV/IM
- Common Trade Names: Dramamine
Adult Dosing
- 50mg PO/IV/IM q4-6h
Pediatric Dosing
- 2-6yo: 12.5-25mg PO q6-8 hrs
- 6-12yo: 25-50mg PO q6-8h
- 1.25 mg/kg IM q6h
Special Populations
- Pregnancy Rating: B
- Lactation risk: Milk effects are posible
- Renal dosing:
- Hepatic dosing: consider dose reduction
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
- Nausea, vomiting
- Sedation
Pharmacology
- Half-life:
- Metabolism: Liver
- Excretion: Renal
Mechanism of Action
- Precise anti-nausea mechanism unknown, has depressant action on hyperstimulated labyrinthine function
Comments
- Dimenhydrinate is a combination drug of diphenhydramine and 8-chlorotheophylline
- Used recreationally as a deliriant[1]
See Also
References
- ↑ Abuse and Misuse Potential of Dimenhydrinate: A Review of the Clinical Evidence. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; December 1, 2015.