Emergency contraception: Difference between revisions

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==Treatment==
==Progestin-Only Regimen==
===Progestin-Only Regimen===
===General===
*First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
*First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
**may take both at once
**may take both at once
*Relative risk reduction of pregnancy = 89% (1% with  vs 8% without)
*Relative risk reduction of pregnancy = 89% (1% with  vs 8% without)
*Side effects
 
**Nausea (23%)
===Adverse Reactions===
**Vomiting (6%)
*Nausea (23%)
*Vomiting (6%)
*No teratogenisis
*No teratogenisis
*FDA approved regimens:
**Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
***Plan B levonorgestrel 0.75mg po q12h x2


===Yuzpe Regimen===
===FDA approved regimens===
(combination OCPs)
*Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
*Yuzpe ethinyl estradiol 100mcg po plus levonorgestral 0.5mg po; repeat in 12h
**Plan B levonorgestrel 0.75mg po q12h x2


==Yuzpe Regimen (Combination OCPs)==
===General===
*First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
*First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
*May be given up to 120 hours later (but efficacy reduced)
*May be given up to 120 hours later (but efficacy reduced)
*Reduces risk of pregnancy by 75% (2% with vs 8% without)
*Reduces risk of pregnancy by 75% (2% with vs 8% without)
*Side effects
 
**Nausea (50%)
===Adverse Reactions===
**Vomiting (20%)
*Nausea (50%)
*Safety
*Vomiting (20%)
**No teratogenic effect
 
*Contraindications
===Safety===
** Pregnancy
*No teratogenic effect
*FDA approved regimens:
 
** Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
===Contraindications===
** Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
* Pregnancy
** Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose
 
** Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
===FDA approved regimens===
* Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h
* Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h
* Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose; repeat in 12h
* Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h
 
==See Also==
*[[Sexual assault]]


==Source==
==Source==


[[Category:OB/GYN]]
[[Category:OB/GYN]]

Revision as of 04:02, 15 January 2015

Progestin-Only Regimen

General

  • First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
    • may take both at once
  • Relative risk reduction of pregnancy = 89% (1% with vs 8% without)

Adverse Reactions

  • Nausea (23%)
  • Vomiting (6%)
  • No teratogenisis

FDA approved regimens

  • Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
    • Plan B levonorgestrel 0.75mg po q12h x2

Yuzpe Regimen (Combination OCPs)

General

  • First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
  • May be given up to 120 hours later (but efficacy reduced)
  • Reduces risk of pregnancy by 75% (2% with vs 8% without)

Adverse Reactions

  • Nausea (50%)
  • Vomiting (20%)

Safety

  • No teratogenic effect

Contraindications

  • Pregnancy

FDA approved regimens

  • Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h
  • Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h
  • Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose; repeat in 12h
  • Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose; repeat in 12h

See Also

Source