Amiodarone: Difference between revisions
| Line 24: | Line 24: | ||
== Adverse Drug Rxns == | == Adverse Drug Rxns == | ||
*Bradycardia, hypotension | *Bradycardia, hypotension | ||
*Prolonged QT | *[[Prolonged QT]] | ||
==See Also== | ==See Also== | ||
Revision as of 21:30, 19 December 2014
Adult Dosing
- V-fib/pulseless V-tach
- Loading dose = 300mg IV bolus followed by 150mg bolus prn
- Stable V-tach or SVT
- Loading dose = 150mg IV in 100mL D5W over 10min
- Follow by infusion of 1mg/min x 6hr; 0.5mg/min thereafter
- Loading dose = 150mg IV in 100mL D5W over 10min
Contraindications
- Iodine or shellfish allergy
- Pregnancy
Indications
- Ventricular and supraventricular arrhythmias
- 1st line for pulseless V-tach/V-fib
- Used for atrial arrhythmias in pts w/ decr EF
Mechanism of Action
- Class III - Inhibits potassium channels
- Impairs SA and AV node conduction
- Decreases automaticity
- Prolongs refractory period in accessory pathways
- Also has class I & II properties
Adverse Drug Rxns
- Bradycardia, hypotension
- Prolonged QT