Etomidate: Difference between revisions
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''See [[critical care quick reference]] for drug doses by weight.'' | |||
==General== | |||
*Type: | |||
*Dosage Forms: | |||
*Common Trade Names: | |||
==Adult Dosing== | |||
===[[RSI]]=== | |||
*0.3 mg/kg bolus IV | |||
*Standard dose = 20mg | |||
===[[Procedural Sedation]]=== | |||
*0.15 mg/kg bolus IV | |||
*Standard dose = 10mg) | |||
==Pediatric Dosing== | |||
''See [[critical care quick reference]] for drug doses by weight.'' | |||
==[[RSI]]== | ==[[RSI]]== | ||
0.3 mg/kg bolus IV | *0.3 mg/kg bolus IV | ||
*Max: 20mg | |||
==[[Procedural Sedation]]== | ==[[Procedural Sedation]]== | ||
0.15 mg/kg bolus IV | *(0.15 mg/kg bolus IV | ||
*Max: 10mg | |||
==Controversy== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | |||
*Lactation: | |||
*Renal Dosing | |||
**Adult | |||
**Pediatric | |||
*Hepatic Dosing | |||
**Adult | |||
**Pediatric | |||
==Contraindications== | |||
*Allergy to class/drug | |||
==Adverse Reactions== | |||
===Controversy=== | |||
"The available evidence suggests that etomidate suppresses adrenal function transiently without | "The available evidence suggests that etomidate suppresses adrenal function transiently without | ||
demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality." | demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality." | ||
== | ==Pharmacology== | ||
*Half-life: | |||
*Metabolism: | |||
*Excretion: | |||
*Mechanism of Action: | |||
==See Also== | ==See Also== | ||
==Sources== | |||
*Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113. | |||
<references/> | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 03:05, 24 February 2015
See critical care quick reference for drug doses by weight.
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
RSI
- 0.3 mg/kg bolus IV
- Standard dose = 20mg
Procedural Sedation
- 0.15 mg/kg bolus IV
- Standard dose = 10mg)
Pediatric Dosing
See critical care quick reference for drug doses by weight.
RSI
- 0.3 mg/kg bolus IV
- Max: 20mg
Procedural Sedation
- (0.15 mg/kg bolus IV
- Max: 10mg
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Controversy
"The available evidence suggests that etomidate suppresses adrenal function transiently without demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.