Template:Acute hepatitis causes: Difference between revisions

Revision as of 18:31, 4 June 2020

Causes of acute hepatitis

Acetaminophen toxicity (most common cause of acute liver failure in the US^[1])
Viral hepatitis
Acute alcoholic hepatitis
Toxins
- Mushroom toxicity
- Crotinarius mushrooms
  - Gyromitra mushrooms
  - Amanita mushrooms
Ischemic hepatitis

↑ Ostapowicz G, Fontana RJ, Schiodt FV, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med. 2002 Dec 17; 137(12): 947-54.

[1] Ostapowicz G, Fontana RJ, Schiodt FV, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med. 2002 Dec 17; 137(12): 947-54.

[1]

@@ Line 8: / Line 8: @@
 **[[Hepatitis E]]
 *[[Acute alcoholic hepatitis]]
+*[[Toxins]]
-*[[Mushroom toxicity]]
+**[[Mushroom toxicity]]
 **[[Crotinarius mushrooms]]
-**[[Gyromitra mushrooms]]
+***[[Gyromitra mushrooms]]
-**[[Amanita mushrooms]]
+***[[Amanita mushrooms]]
 *[[Ischemic hepatitis]]
-===Causes===
-*[[Alcoholic hepatitis]] and other Alcohol-related Liver Disease
-====Drug or Toxin Related Liver Disease====
-*Liver damage from drugs or toxins may be cytotoxic from the primary drug or its metabolites, or may be caused by veno-occlusive disease or hypersensitivity disease<ref>Oyama, LC: Disorders of the Liver and Biliary Tractin Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 107: p 1186-1204</ref>
-*Common Drugs and Toxins
-**[[Acetaminophen]]
-**[[Amiodarone]]
-**[[Amphotericin]]
-**Anabolic steroids
-**[[Azathioprine]]
-**[[Carbamazepine]]
-**[[Chlorpromazine]]
-**Cisplatin
-**Contraceptives
-**[[Cyclophosphamide]]
-**[[Erythromycin]]
-**Gold salts
-**[[Haloperidol]]
-**[[Isoniazid]]
-**[[Ketoconazole]]
-**Lovastatin
-**[[Methotrexate]]
-**Methoxyflurane
-**Methyldopa
-**[[Phenobarbital]]
-**[[Phenytoin]]
-**[[Quinidine]]
-**[[Salicylates]]
-**[[Tetracycline]]
-**[[Valproic acid]]
-**[[Verapamil]]
-===Other Rare Causes of Acute Liver Failure===
-*'''[[Wilson's disease]]''': unexplained elevations in LFTs, neuro-psychiatric symptoms, Kayser-Fleischer rings on eye exam
-*'''[[Autoimmune hepatitis]]''': more common in women, liver disease without explanation, may have family history of other autoimmune disorders
-*'''[[Hemochromatosis]]''': family history of liver disease and cardiac disease
-*'''[[Budd-Chiari]]''': history of hypercoagulable disorder, abdominal pain, and ascites
-*'''Infections''': [[HSV]], [[Epstein-Barr virus]], [[varicella zoster virus]], [[toxoplasmosis]]