Malignant bone tumors: Difference between revisions
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==Differential Diagnosis<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.</ref>== | ==Differential Diagnosis<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.</ref>== | ||
*[[Multiple myeloma]] | *[[Multiple myeloma]] | ||
Revision as of 23:08, 21 November 2019
Differential Diagnosis[1]
| Name | Presentation | Radiograph Findings | Clinical Importance |
| Adamantinoma | Bone pain over anterior tibia in adolescent or young adult | Soap bubble osteolytic appearance on plain radiograph | Metastasis to lungs; may need amputation |
| Chordoma | Constant pain if in sacrum; neurological deficits if at base of skull, most commonly in cranial nerves to the eye | Plain radiograph will show a destructive bone lesion often with an associated soft tissue mass | Slow growing but locally aggressive; metastasis is uncommon, local recurrence is much more likely |
| Fibrosarcoma and Undifferentiated pleomorphic sarcoma | Similar to osteosarcoma except malignant fibroblasts but less common | Most common in distal femur and proximal tibia | Similar outcome to osteosarcoma |
| Primary bone lymphoma | Adult > 40 years of age with bone pain or pathologic fracture | Bone destruction; soft tissue mass | 5 year survival is greater than 50% with radiation and chemotherapy |
Evaluation
Management
Disposition
References
- ↑ Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.