Colestipol: Difference between revisions
(Prepared the page for translation)
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<languages/>
<translate>
==Administration==
==Administration==
*Type: Bile Acid Binder
*Type: Bile Acid Binder
*Dosage Forms: 1 g tab; 5 g/scoop granules; 5 g granule packet
*Dosage Forms: 1 g tab; 5 g/scoop granules; 5 g granule packet
*Routes of Administration: Oral
*Routes of Administration: Oral
*Common Trade Names: N/A
*Common Trade Names: N/A


==Adult Dosing==
==Adult Dosing==
*[[Digoxin toxicity]], adjunct tx
 
*[[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]], adjunct tx
**Granules: 5 g PO q6-8h
**Granules: 5 g PO q6-8h
***Start: 10 g PO x1 within 1-3h after last oral digoxin ingestion
***Start: 10 g PO x1 within 1-3h after last oral digoxin ingestion
***Max: 30 g/day
***Max: 30 g/day
*Gallbladder surgery-associated [[diarrhea]], adjunct tx
*Gallbladder surgery-associated [[Special:MyLanguage/diarrhea|diarrhea]], adjunct tx
**Tabs: 2-16 g/day PO divided QD-QID
**Tabs: 2-16 g/day PO divided QD-QID
***Start: 2 g PO QD-bid
***Start: 2 g PO QD-bid
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***Start: 5 g PO QD-bid
***Start: 5 g PO QD-bid
***Max: 30 g/day
***Max: 30 g/day
*[[Pruritus]] secondary to biliary obstruction
*[[Special:MyLanguage/Pruritus|Pruritus]] secondary to biliary obstruction
**Tabs: 2-16 g/day PO divided QD-QID
**Tabs: 2-16 g/day PO divided QD-QID
***Start: 2 g PO QD-bid
***Start: 2 g PO QD-bid
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***Start: 5 g PO QD-bid
***Start: 5 g PO QD-bid
***Max: 30 g/day
***Max: 30 g/day


==Pediatric Dosing==
==Pediatric Dosing==
Pediatric dosing currently unavailable.
Pediatric dosing currently unavailable.


==Special Populations==
==Special Populations==
*[[Drug pregnancy categories|Pregnancy Rating]]: C; Inadequate data to assess risk
 
*[[Special:MyLanguage/Drug pregnancy categories|Pregnancy Rating]]: C; Inadequate data to assess risk
*Lactation risk: L3; Safety unknown
*Lactation risk: L3; Safety unknown


===Renal Dosing===
===Renal Dosing===
*Adult: No adjustment
*Adult: No adjustment
*Pediatric: N/A
*Pediatric: N/A
===Hepatic Dosing===
===Hepatic Dosing===
*Adult: Not defined.
*Adult: Not defined.
*Pediatric: N/A
*Pediatric: N/A


==Contraindications==
==Contraindications==
*Allergy to class/drug
*Allergy to class/drug
*Caution if constipation
*Caution if constipation
*Caution if prolonged use
*Caution if prolonged use


==Adverse Reactions==
==Adverse Reactions==
===Serious===
===Serious===
*Fecal impaction
*Fecal impaction
*[[PUD]]
*[[Special:MyLanguage/PUD|PUD]]
*[[Cholecystitis]]
*[[Special:MyLanguage/Cholecystitis|Cholecystitis]]
*[[Cholelithiasis]]
*[[Special:MyLanguage/Cholelithiasis|Cholelithiasis]]
*Esophageal obstruction
*Esophageal obstruction


===Common===
===Common===
*[[Constipation]]
 
*[[Special:MyLanguage/Constipation|Constipation]]
*Abdominal pain
*Abdominal pain
*Abdominal cramps
*Abdominal cramps
*Abdominal distention
*Abdominal distention
*Flatulence
*Flatulence
*[[Dyspepsia]]
*[[Special:MyLanguage/Dyspepsia|Dyspepsia]]
*Loose stool/[[Diarrhea]]
*Loose stool/[[Special:MyLanguage/Diarrhea|Diarrhea]]
*[[Nausea]]/[[Vomiting]]
*[[Special:MyLanguage/Nausea|Nausea]]/[[Special:MyLanguage/Vomiting|Vomiting]]
*ALT, AST elevation
*ALT, AST elevation
*Alk Phos. elevation
*Alk Phos. elevation
*Bleeding [[hemorrhoids]]
*Bleeding [[Special:MyLanguage/hemorrhoids|hemorrhoids]]
 


==Pharmacology==
==Pharmacology==
*Half-life: Unknown
*Half-life: Unknown
*Metabolism: N/A
*Metabolism: N/A
*Excretion: Feces
*Excretion: Feces


==Mechanism of Action==
==Mechanism of Action==
Binds intestinal bile acids for excretion.
Binds intestinal bile acids for excretion.


==Comments==
==Comments==
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==See Also==
==See Also==
[[Digoxin toxicity]]
 
[[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]]
 


==References==
==References==
<references/>
<references/>


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[[Category:GI]]
[[Category:GI]]
[[Category:Toxicology]]
[[Category:Toxicology]]
</translate>

Revision as of 21:55, 4 January 2026

Other languages:

Administration

  • Type: Bile Acid Binder
  • Dosage Forms: 1 g tab; 5 g/scoop granules; 5 g granule packet
  • Routes of Administration: Oral
  • Common Trade Names: N/A


Adult Dosing

  • Digoxin toxicity, adjunct tx
    • Granules: 5 g PO q6-8h
      • Start: 10 g PO x1 within 1-3h after last oral digoxin ingestion
      • Max: 30 g/day
  • Gallbladder surgery-associated diarrhea, adjunct tx
    • Tabs: 2-16 g/day PO divided QD-QID
      • Start: 2 g PO QD-bid
      • Max: 16 g/day.
      • Do not crush/cut/chew
    • Granules:5-30 g/day PO divided QD-QID
      • Start: 5 g PO QD-bid
      • Max: 30 g/day
  • Hypercholesterolemia
    • Tabs: 2-16 g/day PO divided QD-QID
      • Start: 2 g PO QD-bid
      • Max: 16 g/day.
      • Do not crush/cut/chew
    • Granules:5-30 g/day PO divided QD-QID
      • Start: 5 g PO QD-bid
      • Max: 30 g/day
  • Pruritus secondary to biliary obstruction
    • Tabs: 2-16 g/day PO divided QD-QID
      • Start: 2 g PO QD-bid
      • Max: 16 g/day.
      • Do not crush/cut/chew
    • Granules:5-30 g/day PO divided QD-QID
      • Start: 5 g PO QD-bid
      • Max: 30 g/day


Pediatric Dosing

Pediatric dosing currently unavailable.


Special Populations

  • Pregnancy Rating: C; Inadequate data to assess risk
  • Lactation risk: L3; Safety unknown


Renal Dosing

  • Adult: No adjustment
  • Pediatric: N/A

Hepatic Dosing

  • Adult: Not defined.
  • Pediatric: N/A


Contraindications

  • Allergy to class/drug
  • Caution if constipation
  • Caution if prolonged use


Adverse Reactions

Serious


Common


Pharmacology

  • Half-life: Unknown
  • Metabolism: N/A
  • Excretion: Feces


Mechanism of Action

Binds intestinal bile acids for excretion.


Comments

See Also

Digoxin toxicity


References

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