Procedures in patients with coagulopathies: Difference between revisions

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==Thoracentesis==
==Thoracentesis==
*Consider transfusion if platelets <50,000, or if PT/PTT twice the normal range <ref>McVay P. et al. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion. 1991 Feb;31(2):164-71</ref>
*Consider transfusion of platelets if platelets <50,000, or Fresh Frozen Plasma if PT/PTT twice the normal range <ref>McVay P. et al. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion. 1991 Feb;31(2):164-71</ref>


==Lumbar Puncture==
==Lumbar Puncture==

Revision as of 14:40, 3 July 2014

Paracentesis

  • Coagulation studies are NOT required before performance of the procedure[1]
    • no data supporting cutoff values for coags/platelets beyond which paracent should be avoided/prophylactically transfused
    • routine use of FFP and platelets is not recommended
  • contraindicated only if DIC or fibrinolysis
  • incidence of clinically significant bleeding complications low even in liver failure (< 0.2%)
  • Greatly increased serum creatinine levels --> consider post-procedure observation

Thoracentesis

  • Consider transfusion of platelets if platelets <50,000, or Fresh Frozen Plasma if PT/PTT twice the normal range [2]

Lumbar Puncture

  • Tranfuse if platelets <50,000[3][4] or INR >1.4[5]
  • If hemophiliac, replace factor before LP

Central Line

  • No benefit FFP if artery isn't hit[6]
  • Consider transfuse if plat <50,000
  • Use compressible site if coagulopathic (jury is still out)

See Also

Sources

  • Paracentesis: Kaji Questions, Thomsen TW. Paracentesis. N Engl J Med 2006; 355: e21.
  • Roberts, Clin Proc Emer Med 2004; Yu (Clin Liv Dz '01)
  1. Wilkerson, Annals of Emerg Med, 2009
  2. McVay P. et al. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion. 1991 Feb;31(2):164-71
  3. Roberts, Clin Proc Emer Med 2004
  4. Johnson KS, et al. Lumbar puncture: Technique, indications, contradindications, and complications in adults. Sept 18, 2013. UpToDate.
  5. Johnson KS, et al. Lumbar puncture: Technique, indications, contradindications, and complications in adults. Sept 18, 2013. UpToDate.
  6. Am J Surg '01