Babesiosis: Difference between revisions
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=Background= | ==Background== | ||
*Spread by the deer tick (Ixodes scapularis) | *Spread by the deer tick (Ixodes scapularis) | ||
**People often unaware they are bitten | **People often unaware they are bitten | ||
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**Babesia Microti is pathogen in US | **Babesia Microti is pathogen in US | ||
=Symptoms= | ==Symptoms== | ||
**Fever, hemolytic anemia, chills, thrombocytopenia, DIC | **Fever, hemolytic anemia, chills, thrombocytopenia, DIC | ||
**More severe disease in immunocompromized patients (HIV, Elderly, '''Asplenic''') | **More severe disease in immunocompromized patients (HIV, Elderly, '''Asplenic''') | ||
=Diagnosis= | ==Diagnosis== | ||
*Peripheral blood smear | *Peripheral blood smear | ||
**Shows intracellular parasites | **Shows intracellular parasites | ||
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=Sources= | =Sources= | ||
* | *CDC http://www.cdc.gov/parasites/babesiosis/ | ||
[[Category:ID]] | [[Category:ID]] | ||
Revision as of 01:49, 18 June 2014
Background
- Spread by the deer tick (Ixodes scapularis)
- People often unaware they are bitten
- Natural reservior is the white footed mouse
- Endemic in US, Europe, parts of Russia and China
- Babesia Microti is pathogen in US
Symptoms
- Fever, hemolytic anemia, chills, thrombocytopenia, DIC
- More severe disease in immunocompromized patients (HIV, Elderly, Asplenic)
Diagnosis
- Peripheral blood smear
- Shows intracellular parasites
- Maltese Cross sign
- May need large smear as parasitemia can be as low as 1%
- Can often be confused for malaria parasites
- Shows intracellular parasites
Treatment
- 2 drug regimen for 7-10 days
- Atovaquone (750mg BID) and Azithromycin (500-1000mg on first day, 250-1000mg on subsequent days)
Clindamycin
- 600 mg PO q8h x 7-10 days
- Alt: 300-600mg IV q6h x 7-10 days
- First Dose: 300-600mg IV x 1
- Give with Quinine (650mg TID); use IV for severe infections