Plague: Difference between revisions
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==Sources== | ==Sources== | ||
Tintinalli | Tintinalli | ||
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Revision as of 04:26, 1 June 2014
Background
- The plague is a severe, acute infection caused by Gram Negative bacillus, Yersinia pestis.
- Two main forms are bubonic and pulmonic forms
- Considered a Class A bioterrorism agent
Clinical Features
Bubonic plague
- Eschar often forms at site of vector bite (usually flea bite)
- Buboes (inflamed, necrotic or hemorrhagic lymph nodes) are pathognomonic
- Liver and splenic involvement
- Septicemia
- Death if untreated in 2-10 days
Pulmonic plague
- Hemoptysis
- Mulilobar hemorrhagic pneumonia
- Sepsis
- Death if untreated in 48 hours
Differential Diagnosis
Management
- Place in isolation
- Treatment should be started within 24 hours of symptoms one of these abx:
- Doxycyline 100mg PO/IV BID
- Ciprofloxacin
- Gentamicin 2mg/kg IV load then 1.7mg/kg TID x 10-14days
Disposition
- Plague is a reportable disease to the CDC
- If bioterrorism suspected, health authorities must be contacted immediately
See Also
Sources
Tintinalli