Anion Gap (Low): Difference between revisions

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***Leads to overestimation of plasma Cl conc)
***Leads to overestimation of plasma Cl conc)
**Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
**Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
 
***Machine mistakenly reads Br as Cl


*AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration
*AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration

Revision as of 00:51, 27 April 2011

Background

  • < 7 meq/L

DDX

  • Lab error
  • Decreased "unmeasured" anions
    • hypoalbuminemia
  • Increased "unmeasured" cations
    • hyperkalemia
    • hypercalcemia
    • hypermagnesemia
    • lithium intoxication
  • Increased cationic paraprotein
    • multiple myeloma
    • polyclonal IgG gammopathy
  • Pseudo
    • Severe hypernatremia (>170 meq/L)
      • True conc of Na is underestimated
    • Marked hyperlipidemia
      • Leads to overestimation of plasma Cl conc)
    • Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
      • Machine mistakenly reads Br as Cl
  • AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration

Source

Kaji Questions