Ertapenem: Difference between revisions
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Revision as of 04:01, 25 March 2014
General
- Type: Carbapenems
- Dosage Forms: IM, IV
- Common Trade Names: Invanz
Adult Dosing
General
- 1g IM/IV daily x 5-14 days
- First Dose: 1g IM/IV x 1
Specific Indications
- 1g IM/IV daily for all
- Intrabdominal infections x 5-14 days
- Skin infections = x 7-14 days
- Pneumonia, community aquired x 10-14 days
- UTI, complicated = x 10-14 days
- Gynecologic = x 3-10 days
- Prophylaxis, colorectal surg = x 1 dose
Pediatric Dosing
General (3mo-12 years)
- 30 mg/kg/day IM/IV divided BID x 5-14 days
- First Dose: 15 mg/kg IM/IV x 1
- Max: 1 g/day
- For duration, see adult specific indication dosing
General (>13 Years)
See adult dosing
Special Populations
- Pregnancy: B
- Lactation: Safety unknown
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
- Hypersensitivity to amide anesthetics (IM only)
Adverse Reactions
Serious
- Hypersensitivity Reaction
- Anaphylaxis
- Neurotoxicity
- [{Seizures]]
- C. diff
- Superinfection
- Extravasation with tissue damage
- Hallucinations
- Hypertension
- Tachycardia
- Drug rash with eosinophilia
Common
- Diarrhea
- Infusion site reaction
- Nausea and Vomiting
- Transaminitis
- Headache
- Fever
- Altered Mental Status
- Constipation
- Abdominal Pain
- Edema
- Insomnia
- Thrombocytosis
- Dyspnea
- Rash
- Dizziness
- Puritis
- Hypotension
- Vaginitis
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Source
- Epocrates