EBQ:MATTERs Study: Difference between revisions
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==Further Reading== | ==Further Reading== | ||
[[EBQ:CRASH-2_Trial]] | [[EBQ:CRASH-2_Trial | CRASH-2 Trial]] | ||
==Sources== | ==Sources== | ||
Revision as of 17:17, 10 March 2014
Under Review Journal Club Article
Morrison J. et al. "Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study". JAMA Surgery. 2012. 147(2):113-119.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Does administration of Tranexamic (TXA) acid in trauma patients with hemorrhage improve mortality in a wartime setting?
Conclusion
The use of TXA with blood component-based resuscitation following combat injury results in improved measures of coagulopathy and survival, a benefit that is most prominent in patients requiring massive transfusion