EBQ:CRASH-2 Trial: Difference between revisions
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==Study Design== | ==Study Design== | ||
*Multicenter, randomized, placebo-controlled trial | |||
==Inclusion Criteria== | ==Inclusion Criteria== | ||
Revision as of 21:40, 16 February 2014
Under Review Journal Club Article
Shakur H, et al. "Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage". The Lancet. 2010. 376(9734):23-32.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Does administration of tranexamic acid reduce the risk of death if administered early in severe trauma?
Conclusion
Tranexamic acid improves survival when administered in less than 3 hrs after injury in patients with significant hemorrhage.
Major Points
Study Design
- Multicenter, randomized, placebo-controlled trial