Anthrax: Difference between revisions
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Gm positive rod, tough spores | Gm positive rod, tough spores | ||
Inhalational Anthrax: Russian accident at Sverdlovsk | Inhalational Anthrax: Russian accident at Sverdlovsk | ||
-Incubation Period is 10 days | -Incubation Period is 10 days | ||
-No one < 24 died | -No one < 24 died | ||
==Ddx== | ==Ddx== | ||
Cutaneous (painless): | Cutaneous (painless): | ||
-Ecthyma gangrenosum | -Ecthyma gangrenosum | ||
-Rat-bite fever (Streptobacillus monilifomis and Spirillum minus) | -Rat-bite fever (Streptobacillus monilifomis and Spirillum minus) | ||
-Ulceroglandular tularemia | -Ulceroglandular tularemia | ||
-Plague | -Plague | ||
-Glanders (Pseudomonas peudomallei) | -Glanders (Pseudomonas peudomallei) | ||
-Rickettsialpox (Rickettsia akari) | -Rickettsialpox (Rickettsia akari) | ||
-Orf (parapox virus) | -Orf (parapox virus) | ||
-Staph lymphadenitis | -Staph lymphadenitis | ||
-TB | -TB | ||
-Leprosy | -Leprosy | ||
-Buruli ulcer (Mycobact ulcerans) | -Buruli ulcer (Mycobact ulcerans) | ||
Inhalational: | Inhalational: | ||
-Acute bacterial mediastinitis | -Acute bacterial mediastinitis | ||
-Mycoplasma | -Mycoplasma | ||
-Legionnaire's | -Legionnaire's | ||
-Psittacosis | -Psittacosis | ||
-Tularemia | -Tularemia | ||
-Q fever (Coxiella burnetti) | -Q fever (Coxiella burnetti) | ||
-Viral pneumonia | -Viral pneumonia | ||
-Histoplasmosis | -Histoplasmosis | ||
-Coccidiomycosis | -Coccidiomycosis | ||
-Ruptured aortic aneurysm | -Ruptured aortic aneurysm | ||
-SVC syndrome | -SVC syndrome | ||
-Silicosis | -Silicosis | ||
-Sarcoidosis | -Sarcoidosis | ||
==Imaging== | ==Imaging== | ||
CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis | CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis | ||
==Treatment== | ==Treatment== | ||
Cipro 500 mg bid or 30 mg/kg div q12 | Cipro 500 mg bid or 30 mg/kg div q12 | ||
Levo 500 mg qd | Levo 500 mg qd | ||
Doxycycline 100 mg bid | Doxycycline 100 mg bid | ||
x 60 days | x 60 days | ||
PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks | PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks | ||
==Source == | ==Source == | ||
7/2/09 PANI | 7/2/09 PANI | ||
Revision as of 22:10, 29 October 2010
Background
Gm positive rod, tough spores
Inhalational Anthrax: Russian accident at Sverdlovsk
-Incubation Period is 10 days
-No one < 24 died
Ddx
Cutaneous (painless):
-Ecthyma gangrenosum
-Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)
-Ulceroglandular tularemia
-Plague
-Glanders (Pseudomonas peudomallei)
-Rickettsialpox (Rickettsia akari)
-Orf (parapox virus)
-Staph lymphadenitis
-TB
-Leprosy
-Buruli ulcer (Mycobact ulcerans)
Inhalational:
-Acute bacterial mediastinitis
-Mycoplasma
-Legionnaire's
-Psittacosis
-Tularemia
-Q fever (Coxiella burnetti)
-Viral pneumonia
-Histoplasmosis
-Coccidiomycosis
-Ruptured aortic aneurysm
-SVC syndrome
-Silicosis
-Sarcoidosis
Imaging
CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis
Treatment
Cipro 500 mg bid or 30 mg/kg div q12
Levo 500 mg qd
Doxycycline 100 mg bid
x 60 days
PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks
Source
7/2/09 PANI