Babesiosis: Difference between revisions
| Line 19: | Line 19: | ||
=Treatment= | =Treatment= | ||
*2 drug regimen for 7-10 days | *2 drug regimen for 7-10 days | ||
**Atovaquone (750mg BID) and Azithromycin (500-1000mg on first day, 250-1000mg on subsequent days) | **Atovaquone (750mg BID) and [[Azithromycin]] (500-1000mg on first day, 250-1000mg on subsequent days) | ||
**Clindamycin (600mg PO TID or 300-600mg IV QID) and Quinine (650mg TID) | **[[Clindamycin]] (600mg PO TID or 300-600mg IV QID) and Quinine (650mg TID) | ||
==See Also== | ==See Also== | ||
Revision as of 19:23, 27 March 2014
Background
- Spread by the deer tick (Ixodes scapularis)
- People often unaware they are bitten
- Natural reservior is the white footed mouse
- Endemic in US, Europe, parts of Russia and China
- Babesia Microti is pathogen in US
Symptoms
- Fever, hemolytic anemia, chills, thrombocytopenia, DIC
- More severe disease in immunocompromized patients (HIV, Elderly, Asplenic)
Diagnosis
- Peripheral blood smear
- Shows intracellular parasites
- Maltese Cross sign
- May need large smear as parasitemia can be as low as 1%
- Can often be confused for malaria parasites
- Shows intracellular parasites
Treatment
- 2 drug regimen for 7-10 days
- Atovaquone (750mg BID) and Azithromycin (500-1000mg on first day, 250-1000mg on subsequent days)
- Clindamycin (600mg PO TID or 300-600mg IV QID) and Quinine (650mg TID)
See Also
Sources
- Wikipedia
- cdc.gov/parastites/babesiosis